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Exploring the signaling space of a GPCR using bivalent ligands with a rigid oligoproline backbone.
Romantini, Nina; Alam, Shahidul; Dobitz, Stefanie; Spillmann, Martin; De Foresta, Martina; Schibli, Roger; Schertler, Gebhard F X; Wennemers, Helma; Deupi, Xavier; Behe, Martin; Berger, Philipp.
Afiliação
  • Romantini N; Center for Radiopharmaceutical Sciences, Paul Scherrer Institute, CH-5232 Villigen, Switzerland.
  • Alam S; Center for Radiopharmaceutical Sciences, Paul Scherrer Institute, CH-5232 Villigen, Switzerland.
  • Dobitz S; Laboratory of Nanoscale Biology, Paul Scherrer Institute, CH-5232 Villigen, Switzerland.
  • Spillmann M; Laboratory of Organic Chemistry, ETH Zürich, CH-8093 Zürich, Switzerland.
  • De Foresta M; Laboratory of Nanoscale Biology, Paul Scherrer Institute, CH-5232 Villigen, Switzerland.
  • Schibli R; Laboratory of Organic Chemistry, ETH Zürich, CH-8093 Zürich, Switzerland.
  • Schertler GFX; Center for Radiopharmaceutical Sciences, Paul Scherrer Institute, CH-5232 Villigen, Switzerland.
  • Wennemers H; Department of Biology and Chemistry, Paul Scherrer Institute, CH-5232 Villigen, Switzerland.
  • Deupi X; Laboratory of Organic Chemistry, ETH Zürich, CH-8093 Zürich, Switzerland.
  • Behe M; Laboratory of Biomolecular Research, Paul Scherrer Institute, CH-5232 Villigen, Switzerland.
  • Berger P; Condensed Matter Theory Group, Paul Scherrer Institute, CH-5232 Villigen, Switzerland.
Proc Natl Acad Sci U S A ; 118(48)2021 11 30.
Article em En | MEDLINE | ID: mdl-34810259
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Prolina / Receptores Acoplados a Proteínas G Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Prolina / Receptores Acoplados a Proteínas G Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article