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LipE guided discovery of isopropylphenyl pyridazines as pantothenate kinase modulators.
Sharma, Lalit Kumar; Yun, Mi Kyung; Subramanian, Chitra; Tangallapally, Rajendra; Jackowski, Suzanne; Rock, Charles O; White, Stephen W; Lee, Richard E.
Afiliação
  • Sharma LK; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, 262 Danny Thomas PI, MS1000, Memphis, TN 38105, United States; Department of Infectious Diseases, St. Jude Children's Research Hospital, United States.
  • Yun MK; Department of Structural Biology, St. Jude Children's Research Hospital, United States.
  • Subramanian C; Department of Infectious Diseases, St. Jude Children's Research Hospital, United States.
  • Tangallapally R; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, 262 Danny Thomas PI, MS1000, Memphis, TN 38105, United States.
  • Jackowski S; Department of Infectious Diseases, St. Jude Children's Research Hospital, United States.
  • Rock CO; Department of Infectious Diseases, St. Jude Children's Research Hospital, United States.
  • White SW; Department of Structural Biology, St. Jude Children's Research Hospital, United States.
  • Lee RE; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, 262 Danny Thomas PI, MS1000, Memphis, TN 38105, United States. Electronic address: Richard.Lee@stjude.org.
Bioorg Med Chem ; 52: 116504, 2021 12 15.
Article em En | MEDLINE | ID: mdl-34814071
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piridazinas / Fosfotransferases (Aceptor do Grupo Álcool) / Descoberta de Drogas / Ensaios de Triagem em Larga Escala Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piridazinas / Fosfotransferases (Aceptor do Grupo Álcool) / Descoberta de Drogas / Ensaios de Triagem em Larga Escala Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article