hnRNPU in Sertoli cells cooperates with WT1 and is essential for testicular development by modulating transcriptional factors <i>Sox8/9</i>.

Wen, Yujiao; Ma, Xixiang; Wang, Xiaoli; Wang, Fengli; Dong, Juan; Wu, Yanqing; Lv, Chunyu; Liu, Kuan; Zhang, Yan; Zhang, Zhibing; Yuan, Shuiqiao

hnRNPU in Sertoli cells cooperates with WT1 and is essential for testicular development by modulating transcriptional factors Sox8/9.

Wen, Yujiao; Ma, Xixiang; Wang, Xiaoli; Wang, Fengli; Dong, Juan; Wu, Yanqing; Lv, Chunyu; Liu, Kuan; Zhang, Yan; Zhang, Zhibing; Yuan, Shuiqiao.

Afiliação

Wen Y; Institute of Reproductive Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China.
Ma X; Institute of Reproductive Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China.
Wang X; Institute of Reproductive Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China.
Wang F; Institute of Reproductive Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China.
Dong J; Institute of Reproductive Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China.
Wu Y; Institute of Reproductive Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China.
Lv C; Institute of Reproductive Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China.
Liu K; Institute of Reproductive Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China.
Zhang Y; Institute of Reproductive Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China.
Zhang Z; Department of Obstetrics & Gynecology, Wayne State University, Detroit, MI 48201, USA.
Yuan S; Department of Physiology, Wayne State University, Detroit, MI 48201, USA.

Theranostics ; 11(20): 10030-10046, 2021.

Article em En | MEDLINE | ID: mdl-34815802

Assuntos

Ribonucleoproteínas Nucleares Heterogêneas Grupo U/metabolismo; Células de Sertoli/metabolismo; Proteínas WT1/metabolismo; Animais; Diferenciação Celular/genética; Expressão Gênica/genética; Regulação da Expressão Gênica/genética; Ribonucleoproteínas Nucleares Heterogêneas Grupo U/genética; Humanos; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Fatores de Transcrição SOX9/metabolismo; Fatores de Transcrição SOXE/metabolismo; Testículo/embriologia; Testículo/metabolismo; Fatores de Transcrição/genética; Transcriptoma/genética; Proteínas WT1/genética

Palavras-chave

Mice; Sertoli cells; Testicular development; Transcription factor; hnRNPU

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células de Sertoli / Proteínas WT1 / Ribonucleoproteínas Nucleares Heterogêneas Grupo U Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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