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Alpha-synuclein from patient Lewy bodies exhibits distinct pathological activity that can be propagated in vitro.
Marotta, Nicholas P; Ara, Jahan; Uemura, Norihito; Lougee, Marshall G; Meymand, Emily S; Zhang, Bin; Petersson, E James; Trojanowski, John Q; Lee, Virginia M-Y.
Afiliação
  • Marotta NP; Department of Pathology and Laboratory Medicine, Institute on Aging and Center for Neurodegenerative Disease Research, University of Pennsylvania School of Medicine, Philadelphia, PA, 19104, USA.
  • Ara J; Department of Pathology and Laboratory Medicine, Institute on Aging and Center for Neurodegenerative Disease Research, University of Pennsylvania School of Medicine, Philadelphia, PA, 19104, USA.
  • Uemura N; Department of Pathology and Laboratory Medicine, Institute on Aging and Center for Neurodegenerative Disease Research, University of Pennsylvania School of Medicine, Philadelphia, PA, 19104, USA.
  • Lougee MG; Department of Chemistry, University of Pennsylvania School of Arts and Sciences, Philadelphia, PA, 19104, USA.
  • Meymand ES; Department of Pathology and Laboratory Medicine, Institute on Aging and Center for Neurodegenerative Disease Research, University of Pennsylvania School of Medicine, Philadelphia, PA, 19104, USA.
  • Zhang B; Department of Pathology and Laboratory Medicine, Institute on Aging and Center for Neurodegenerative Disease Research, University of Pennsylvania School of Medicine, Philadelphia, PA, 19104, USA.
  • Petersson EJ; Department of Chemistry, University of Pennsylvania School of Arts and Sciences, Philadelphia, PA, 19104, USA.
  • Trojanowski JQ; Department of Pathology and Laboratory Medicine, Institute on Aging and Center for Neurodegenerative Disease Research, University of Pennsylvania School of Medicine, Philadelphia, PA, 19104, USA.
  • Lee VM; Department of Pathology and Laboratory Medicine, Institute on Aging and Center for Neurodegenerative Disease Research, University of Pennsylvania School of Medicine, Philadelphia, PA, 19104, USA. vmylee@upenn.edu.
Acta Neuropathol Commun ; 9(1): 188, 2021 11 24.
Article em En | MEDLINE | ID: mdl-34819159

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Corpos de Lewy / Alfa-Sinucleína Tipo de estudo: Risk_factors_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Corpos de Lewy / Alfa-Sinucleína Tipo de estudo: Risk_factors_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article