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An activity-based bioprobe differentiates a novel small molecule inhibitor from a LOXL2 antibody and provides renewed promise for anti-fibrotic therapeutic strategies.
Findlay, Alison; Turner, Craig; Schilter, Heidi; Deodhar, Mandar; Zhou, Wenbin; Perryman, Lara; Foot, Jonathan; Zahoor, Amna; Yao, Yimin; Hamilton, Ross; Brock, Mary; Raso, Christina; Stolp, Jessica; Galati, Marie; Hamprecht, Dieter; Charlton, Brett; Jarolimek, Wolfgang.
Afiliação
  • Findlay A; Pharmaxis, Frenchs Forest, New South Wales, Australia.
  • Turner C; Pharmaxis, Frenchs Forest, New South Wales, Australia.
  • Schilter H; Pharmaxis, Frenchs Forest, New South Wales, Australia.
  • Deodhar M; Pharmaxis, Frenchs Forest, New South Wales, Australia.
  • Zhou W; Pharmaxis, Frenchs Forest, New South Wales, Australia.
  • Perryman L; Pharmaxis, Frenchs Forest, New South Wales, Australia.
  • Foot J; Pharmaxis, Frenchs Forest, New South Wales, Australia.
  • Zahoor A; Pharmaxis, Frenchs Forest, New South Wales, Australia.
  • Yao Y; Pharmaxis, Frenchs Forest, New South Wales, Australia.
  • Hamilton R; Pharmaxis, Frenchs Forest, New South Wales, Australia.
  • Brock M; Quanterix, Billerica, Massachusetts, USA.
  • Raso C; Quanterix, Billerica, Massachusetts, USA.
  • Stolp J; Pharmaxis, Frenchs Forest, New South Wales, Australia.
  • Galati M; Pharmaxis, Frenchs Forest, New South Wales, Australia.
  • Hamprecht D; Pharmaxis, Frenchs Forest, New South Wales, Australia.
  • Charlton B; Pharmaxis, Frenchs Forest, New South Wales, Australia.
  • Jarolimek W; Pharmaxis, Frenchs Forest, New South Wales, Australia.
Clin Transl Med ; 11(11): e572, 2021 11.
Article em En | MEDLINE | ID: mdl-34841699
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Técnicas Biossensoriais / Antifibróticos / Aminoácido Oxirredutases Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Técnicas Biossensoriais / Antifibróticos / Aminoácido Oxirredutases Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article