Comprehensive analysis of miRNA-mRNA regulatory network and potential drugs in chronic chagasic cardiomyopathy across human and mouse.

Wu, Jiahe; Cao, Jianlei; Fan, Yongzhen; Li, Chenze; Hu, Xiaorong

Wu, Jiahe; Cao, Jianlei; Fan, Yongzhen; Li, Chenze; Hu, Xiaorong.

Afiliação

Wu J; Department of Cardiology, Zhongnan Hospital of Wuhan University, No. 169 Donghu Road, Wuchang District, Wuhan, 430071, China.
Cao J; Institute of Myocardial Injury and Repair, Wuhan University, Wuhan, China.
Fan Y; Department of Cardiology, Zhongnan Hospital of Wuhan University, No. 169 Donghu Road, Wuchang District, Wuhan, 430071, China. cjlzn14@whu.edu.cn.
Li C; Institute of Myocardial Injury and Repair, Wuhan University, Wuhan, China. cjlzn14@whu.edu.cn.
Hu X; Department of Cardiology, Zhongnan Hospital of Wuhan University, No. 169 Donghu Road, Wuchang District, Wuhan, 430071, China.

BMC Med Genomics ; 14(1): 283, 2021 11 29.

Article em En | MEDLINE | ID: mdl-34844599

Assuntos

Cardiomiopatias; Proteínas Imediatamente Precoces; MicroRNAs; Animais; Redes Reguladoras de Genes; Humanos; Proteínas Imediatamente Precoces/genética; Proteínas de Membrana/genética; Camundongos; MicroRNAs/genética; Proteínas dos Microfilamentos/genética; Fosfatidilinositol 3-Quinases/genética; RNA Mensageiro/genética; Inibidor beta de Dissociação do Nucleotídeo Guanina rho/genética

Palavras-chave

Bioinformatics analysis; Chronic chagasic cardiomyopathy; Gene function enrichment analysis; Hub gene; PPI network; miRNAmRNA regulatory network

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Imediatamente Precoces / MicroRNAs / Cardiomiopatias Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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