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Niclosamide shows strong antiviral activity in a human airway model of SARS-CoV-2 infection and a conserved potency against the Alpha (B.1.1.7), Beta (B.1.351) and Delta variant (B.1.617.2).
Weiss, Anne; Touret, Franck; Baronti, Cecile; Gilles, Magali; Hoen, Bruno; Nougairède, Antoine; de Lamballerie, Xavier; Sommer, Morten O A.
Afiliação
  • Weiss A; UNION therapeutics Research Services, Hellerup, Denmark.
  • Touret F; Novo Nordisk Center for Biosustainability, Technical University Denmark, Lyngby, Denmark.
  • Baronti C; Unité des Virus Émergents (UVE: Aix-Marseille University -IRD 190-Inserm 1207-IHU Méditerranée, Infection), Marseille, France.
  • Gilles M; Unité des Virus Émergents (UVE: Aix-Marseille University -IRD 190-Inserm 1207-IHU Méditerranée, Infection), Marseille, France.
  • Hoen B; Unité des Virus Émergents (UVE: Aix-Marseille University -IRD 190-Inserm 1207-IHU Méditerranée, Infection), Marseille, France.
  • Nougairède A; Institute Pasteur, Paris, France.
  • de Lamballerie X; Unité des Virus Émergents (UVE: Aix-Marseille University -IRD 190-Inserm 1207-IHU Méditerranée, Infection), Marseille, France.
  • Sommer MOA; Unité des Virus Émergents (UVE: Aix-Marseille University -IRD 190-Inserm 1207-IHU Méditerranée, Infection), Marseille, France.
PLoS One ; 16(12): e0260958, 2021.
Article em En | MEDLINE | ID: mdl-34855904
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / SARS-CoV-2 / Tratamento Farmacológico da COVID-19 / Niclosamida Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / SARS-CoV-2 / Tratamento Farmacológico da COVID-19 / Niclosamida Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article