Towards tolerance in liver transplantation.
Best Pract Res Clin Gastroenterol
; 54-55: 101770, 2021.
Article
em En
| MEDLINE
| ID: mdl-34874844
ABSTRACT
Life-long immunosuppression has always been considered the key in managing liver graft protection from recipient rejection. However, it is associated with severe adverse effects that lead to increased morbidity and mortality, including infections, cardiovascular diseases, kidney failure, metabolic disorders and de novo malignancies. This explains the great interest that has developed in the concept of tolerance in recent years. The liver, thanks to its marked tolerogenicity, is to be considered a privileged organ up to 60% of selected patients undergoing liver transplantation could safely withdraw immunosuppression.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transplante de Fígado
Limite:
Humans
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article