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Nm23-H1 activator phenylbutenoid dimer exerts cytotoxic effects on metastatic breast cancer cells by inducing mitochondrial dysfunction only under glucose starvation.
Kim, Bokyung; Lee, Jae-Jin; Shin, Ji Soo; Suh, Ji-Wan; Jung, Sunhee; Hwang, Geum-Sook; Lee, Hee-Yoon; Lee, Kong-Joo.
Afiliação
  • Kim B; College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, 03760, Korea.
  • Lee JJ; College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, 03760, Korea.
  • Shin JS; Department of Chemistry, Korea Advanced Institute of Science and Technology, Daejeon, 34051, Korea.
  • Suh JW; College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, 03760, Korea.
  • Jung S; Integrated Metabolomics Research Group, Western Seoul Center, Korea Basic Science Institute, Seoul, 03759, Korea.
  • Hwang GS; Integrated Metabolomics Research Group, Western Seoul Center, Korea Basic Science Institute, Seoul, 03759, Korea.
  • Lee HY; Department of Chemistry, Korea Advanced Institute of Science and Technology, Daejeon, 34051, Korea. leehy@kaist.ac.kr.
  • Lee KJ; College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, 03760, Korea. kjl@ewha.ac.kr.
Sci Rep ; 11(1): 23549, 2021 12 07.
Article em En | MEDLINE | ID: mdl-34876614
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estirenos / Neoplasias da Mama / Cicloexenos / Nucleosídeo NM23 Difosfato Quinases / Antineoplásicos Limite: Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estirenos / Neoplasias da Mama / Cicloexenos / Nucleosídeo NM23 Difosfato Quinases / Antineoplásicos Limite: Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article