Cytoskeletal protein degradation in brain death donor kidneys associates with adverse posttransplant outcomes.

Vaughan, Rebecca H; Kresse, Jean-Claude; Farmer, Louise K; Thézénas, Marie L; Kessler, Benedikt M; Lindeman, Jan H N; Sharples, Edward J; Welsh, Gavin I; Nørregaard, Rikke; Ploeg, Rutger J; Kaisar, Maria

Vaughan, Rebecca H; Kresse, Jean-Claude; Farmer, Louise K; Thézénas, Marie L; Kessler, Benedikt M; Lindeman, Jan H N; Sharples, Edward J; Welsh, Gavin I; Nørregaard, Rikke; Ploeg, Rutger J; Kaisar, Maria.

Afiliação

Vaughan RH; Research and Development, NHS Blood and Transplant, Bristol & Oxford, UK.
Kresse JC; Nuffield Department of Surgical Sciences, Oxford University Hospital Oxford, Biomedical Research Centre, University of Oxford, Oxford, UK.
Farmer LK; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Thézénas ML; Bristol Renal, Bristol Medical School, University of Bristol, Bristol, UK.
Kessler BM; Nuffield Department of Medicine, Target Discovery Institute, University of Oxford, Oxford, UK.
Lindeman JHN; Nuffield Department of Medicine, Target Discovery Institute, University of Oxford, Oxford, UK.
Sharples EJ; Department of Surgery, Leiden University Medical Centre, Leiden, The Netherlands.
Welsh GI; Oxford University Hospital, Oxford, UK.
Nørregaard R; Bristol Renal, Bristol Medical School, University of Bristol, Bristol, UK.
Ploeg RJ; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Kaisar M; Research and Development, NHS Blood and Transplant, Bristol & Oxford, UK.

Am J Transplant ; 22(4): 1073-1087, 2022 04.

Article em En | MEDLINE | ID: mdl-34878723

Assuntos

Transplante de Rim; Obtenção de Tecidos e Órgãos; Morte Encefálica/patologia; Proteínas do Citoesqueleto; Sobrevivência de Enxerto; Humanos; Rim/patologia; Transplante de Rim/efeitos adversos; Transplante de Rim/métodos; Doadores Vivos; Proteólise; Doadores de Tecidos

Palavras-chave

QUOD biobank; basic (laboratory) research/science; cellular biology; donors and donation: donation after brain death (DBD); glomerular biology and disease; kidney (allograft) function/dysfunction; kidney failure/injury; kidney transplantation/nephrology; organ transplantation in general; proteomics; translational research/science

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Obtenção de Tecidos e Órgãos / Transplante de Rim Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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