Neuroprotective effects of synthetic borneol and natural borneol based on the neurovascular unit against cerebral ischaemic injury.

Xie, Qian; Li, Jinxiu; Dong, Taiwei; Yuan, Jianmei; Lu, Danni; Ma, Rong; Li, Hongyan; Li, Yong; Ren, Mihong; Chen, Hai; Wang, Jian

Xie, Qian; Li, Jinxiu; Dong, Taiwei; Yuan, Jianmei; Lu, Danni; Ma, Rong; Li, Hongyan; Li, Yong; Ren, Mihong; Chen, Hai; Wang, Jian.

Afiliação

Xie Q; State Key Laboratory of Characteristic Chinese Medicine Resources in Southwest China, Chengdu, P.R. China.
Li J; School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, P.R. China.
Dong T; State Key Laboratory of Characteristic Chinese Medicine Resources in Southwest China, Chengdu, P.R. China.
Yuan J; School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, P.R. China.
Lu D; College of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, P.R. China.
Ma R; State Key Laboratory of Characteristic Chinese Medicine Resources in Southwest China, Chengdu, P.R. China.
Li H; School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, P.R. China.
Li Y; State Key Laboratory of Characteristic Chinese Medicine Resources in Southwest China, Chengdu, P.R. China.
Ren M; School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, P.R. China.
Chen H; State Key Laboratory of Characteristic Chinese Medicine Resources in Southwest China, Chengdu, P.R. China.
Wang J; School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, P.R. China.

J Pharm Pharmacol ; 74(2): 236-249, 2022 Feb 01.

Article em En | MEDLINE | ID: mdl-34888686

Assuntos

Isquemia Encefálica/tratamento farmacológico; Canfanos/farmacologia; Fármacos Neuroprotetores/farmacologia; Animais; Temperatura Corporal/efeitos dos fármacos; Isquemia Encefálica/patologia; Canfanos/química; Modelos Animais de Doenças; Masculino; Microglia/efeitos dos fármacos; Microscopia Eletrônica de Transmissão; Fármacos Neuroprotetores/química; Ratos; Ratos Sprague-Dawley

Palavras-chave

Notch pathway; middle cerebral artery occlusion model; natural borneol; neuroprotection; neurovascular units; synthetic borneol

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Canfanos / Isquemia Encefálica / Fármacos Neuroprotetores Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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