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Chemoselective Trimerization of Isocyanides: De Novo Synthesis of 2-Indole-Substituted Quinolines and Pyridines.
Bao, Lan; Liu, Yu; Peng, Jinghan; Wang, Yuan; Dong, Jinhuan; Xu, Xianxiu.
Afiliação
  • Bao L; College of Chemistry, Chemical Engineering, and Materials Science; Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong; Key Laboratory of Molecular and Nano Probes, Ministry of Education; Shandong Provincial Key Laboratory of Clean Production of
  • Liu Y; College of Chemistry, Chemical Engineering, and Materials Science; Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong; Key Laboratory of Molecular and Nano Probes, Ministry of Education; Shandong Provincial Key Laboratory of Clean Production of
  • Peng J; College of Chemistry, Chemical Engineering, and Materials Science; Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong; Key Laboratory of Molecular and Nano Probes, Ministry of Education; Shandong Provincial Key Laboratory of Clean Production of
  • Wang Y; College of Chemistry, Chemical Engineering, and Materials Science; Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong; Key Laboratory of Molecular and Nano Probes, Ministry of Education; Shandong Provincial Key Laboratory of Clean Production of
  • Dong J; College of Chemistry, Chemical Engineering, and Materials Science; Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong; Key Laboratory of Molecular and Nano Probes, Ministry of Education; Shandong Provincial Key Laboratory of Clean Production of
  • Xu X; College of Chemistry, Chemical Engineering, and Materials Science; Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong; Key Laboratory of Molecular and Nano Probes, Ministry of Education; Shandong Provincial Key Laboratory of Clean Production of
Org Lett ; 24(1): 105-109, 2022 Jan 14.
Article em En | MEDLINE | ID: mdl-34889616
ABSTRACT
A catalyst-free chemoselective trimerization reaction of readily available isocyanides is described. This domino reaction provides facile access to a wide range of 2-(indol-2-yl)-quinolines and 2-(indol-2-yl)-pyridines in moderate to excellent yields. A "head to head" heterodimerization of two isocyanides is proposed as the key step of this reaction.

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article