Overcoming the impacts of two-step batch effect correction on gene expression estimation and inference.

Li, Tenglong; Zhang, Yuqing; Patil, Prasad; Johnson, W Evan

Li, Tenglong; Zhang, Yuqing; Patil, Prasad; Johnson, W Evan.

Afiliação

Li T; Academy of Pharmacy, Xi'an Jiaotong-Liverpool University, 111 Ren'ai Road, Dushu Lake Higher Education Town, Suzhou Industrial Park, Suzhou 215123, Jiangsu Province, PRC.
Zhang Y; Clinical Bioinformatics, Gilead Sciences, Inc., 333 Lakeside Dr, Foster City, CA 94404.
Patil P; Department of Biostatistics, School of Public Health, 801 Massachusetts Ave. Boston, MA 02118, USA.
Johnson WE; Division of Computational Biomedicine, School of Medicine, 72 E. Concord Street, Boston, MA 02118, USA and Department of Biostatistics, School of Public Health, 801 Massachusetts Ave. Boston, MA 02118, USA.

Biostatistics ; 24(3): 635-652, 2023 Jul 14.

Article em En | MEDLINE | ID: mdl-34893807

Assuntos

Expressão Gênica; Humanos; Filogenia; Projetos de Pesquisa

Palavras-chave

Batch effect; ComBat; Generalized least squares; Sample correlation adjustment; Two-step batch adjustment

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Expressão Gênica Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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