EVALUATION OF HORMONAL FUNCTION IN WOMEN WITH CERVICAL INSUFFICIENCY AND INFERTILITY IN THE HISTORY.
Wiad Lek
; 74(10 pt 1): 2412-2416, 2021.
Article
em En
| MEDLINE
| ID: mdl-34896996
ABSTRACT
OBJECTIVE:
Theaim:
To assess the levels of hormones in women with cervical insufficiency and infertility in the history in the II trimester of gestation. PATIENTS ANDMETHODS:
Materials andmethods:
120 pregnant women with cervical insufficiency and anovulatory infertility in the history were examined in the II trimester of gestation in the I group (60 persons) pregnancy occurred after hormonal treatment of infertility, in the II group (60 individuals) - after in vitro fertilization. 30 pregnant women without cervical insufficiency and a history of infertility were controls. The levels of estradiol, progesterone, placental lactogen, prolactin and cortisol were determined in the blood serum.RESULTS:
Results:
The concentration of maternal progesterone was lower in the persons in the I group on 12.36 %, in the II group - on the 15.37 % (p=0.03) compared to the healthy women. Cortisol and prolactin amounts were statistically higher in I and II groups (p<0.001) than in controls. While the levels of estradiol and placental lactogen were slightly less in the subjects with cervical insufficiency and a history of anovulatory infertility compared to the healthy women.CONCLUSION:
Conclusions:
In pregnant women with cervical insufficiency and a history of anovulatory infertility in the II trimester of gestation there are decrease progesterone level and high prolactin and cortisol concentrations in blood serum. The changes in estradiol and placental lactogen amounts are not significant compared to healthy women.Palavras-chave
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Placenta
/
Infertilidade Feminina
Limite:
Female
/
Humans
/
Pregnancy
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article