The phosphatidylglycerol phosphate synthase PgsA utilizes a trifurcated amphipathic cavity for catalysis at the membrane-cytosol interface.

Yang, Bowei; Yao, Hebang; Li, Dianfan; Liu, Zhenfeng

Yang, Bowei; Yao, Hebang; Li, Dianfan; Liu, Zhenfeng.

Afiliação

Yang B; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.
Yao H; College of Life Sciences, University of Chinese Academy of Sciences, Beijing, 100049, China.
Li D; CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai, 201210, China.
Liu Z; College of Life Sciences, University of Chinese Academy of Sciences, Beijing, 100049, China.

Curr Res Struct Biol ; 3: 312-323, 2021.

Article em En | MEDLINE | ID: mdl-34901881

Palavras-chave

CDP-DAG, cytidine diphosphate-diacylglycerol; CL, cardiolipin; Crystal structure; Daptomycin resistance; G3P, glycerol 3-phosphate; LCP, lipidic cubic phase; MRSA, methicillin-resistant Staphylococcus aureus; Membrane protein; PG, phosphatidylglycerol; PGP, phosphatidylglycerol phosphate; PgsA, phosphatidylglycerol phosphate synthase A; Phosphatidylglycerol; Staphylococcus aureus; Synthase

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article