Development and Application of DropletProbe Mass Spectrometry for Examining Biodistribution of Therapeutics.

Chen, Bingming; Vavrek, Marissa; Cancilla, Mark T; Kertesz, Vilmos

Chen, Bingming; Vavrek, Marissa; Cancilla, Mark T; Kertesz, Vilmos.

Afiliação

Chen B; Department of Preclinical Development, Merck & Co., Inc., Kenilworth, NJ, USA. bingming.chen@merck.com.
Vavrek M; Department of Preclinical Development, Merck & Co., Inc., Kenilworth, NJ, USA.
Cancilla MT; Department of Preclinical Development, Merck & Co., Inc., Kenilworth, NJ, USA.
Kertesz V; Bioanalytical Mass Spectrometry Group, Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN, USA.

Methods Mol Biol ; 2437: 171-180, 2022.

Article em En | MEDLINE | ID: mdl-34902148

Assuntos

Espectrometria de Massas; Animais; Diclofenaco; Camundongos; Microtomia; Distribuição Tecidual

Palavras-chave

Diclofenac; DropletProbe; Mass spectrometry; Metabolite identification; Tissue distribution; Whole-body analysis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Espectrometria de Massas Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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