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The BRCT domain of PARP1 binds intact DNA and mediates intrastrand transfer.
Rudolph, Johannes; Muthurajan, Uma M; Palacio, Megan; Mahadevan, Jyothi; Roberts, Genevieve; Erbse, Annette H; Dyer, Pamela N; Luger, Karolin.
Afiliação
  • Rudolph J; Department of Biochemistry, University of Colorado Boulder, Boulder, CO 80309, USA.
  • Muthurajan UM; Department of Biochemistry, University of Colorado Boulder, Boulder, CO 80309, USA.
  • Palacio M; Department of Biochemistry, University of Colorado Boulder, Boulder, CO 80309, USA.
  • Mahadevan J; Department of Biochemistry, University of Colorado Boulder, Boulder, CO 80309, USA.
  • Roberts G; Department of Biochemistry, University of Colorado Boulder, Boulder, CO 80309, USA.
  • Erbse AH; Department of Biochemistry, University of Colorado Boulder, Boulder, CO 80309, USA.
  • Dyer PN; Howard Hughes Medical Institute, University of Colorado Boulder, Boulder, CO 80309, USA.
  • Luger K; Department of Biochemistry, University of Colorado Boulder, Boulder, CO 80309, USA; Howard Hughes Medical Institute, University of Colorado Boulder, Boulder, CO 80309, USA. Electronic address: karolin.luger@colorado.edu.
Mol Cell ; 81(24): 4994-5006.e5, 2021 12 16.
Article em En | MEDLINE | ID: mdl-34919819
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dano ao DNA / DNA / Nucleossomos / Poli(ADP-Ribose) Polimerase-1 Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dano ao DNA / DNA / Nucleossomos / Poli(ADP-Ribose) Polimerase-1 Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article