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VTT-006, an anti-mitotic compound, binds to the Ndc80 complex and suppresses cancer cell growth in vitro.
Laine, Leena J; Mäki-Jouppila, Jenni H E; Kutvonen, Emma; Tiikkainen, Pekka; Nyholm, Thomas K M; Tien, Jerry F; Umbreit, Neil T; Härmä, Ville; Kallio, Lila; Davis, Trisha N; Asbury, Charles L; Poso, Antti; Gorbsky, Gary J; Kallio, Marko J.
Afiliação
  • Laine LJ; VTT Health, VTT Technical Research Centre of Finland Ltd., Otaniemi, Finland.
  • Mäki-Jouppila JHE; Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku 20520, Finland.
  • Kutvonen E; These authors contributed equally to this work.
  • Tiikkainen P; VTT Health, VTT Technical Research Centre of Finland Ltd., Otaniemi, Finland.
  • Nyholm TKM; Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku 20520, Finland.
  • Tien JF; Drug Research Doctoral Programme, University of Turku, Finland.
  • Umbreit NT; Department of Pharmacology, Drug Development and Therapeutics, University of Turku, Turku, Finland.
  • Härmä V; These authors contributed equally to this work.
  • Kallio L; VTT Health, VTT Technical Research Centre of Finland Ltd., Otaniemi, Finland.
  • Davis TN; Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku 20520, Finland.
  • Asbury CL; VTT Health, VTT Technical Research Centre of Finland Ltd., Otaniemi, Finland.
  • Poso A; Department of Biosciences, Åbo Akademi University, Turku, Finland.
  • Gorbsky GJ; Department of Biochemistry, University of Washington, Seattle, WA, USA.
  • Kallio MJ; Department of Biochemistry, University of Washington, Seattle, WA, USA.
Oncoscience ; 8: 134-153, 2021.
Article em En | MEDLINE | ID: mdl-34926718
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2021 Tipo de documento: Article