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Sarm1 activation produces cADPR to increase intra-axonal Ca++ and promote axon degeneration in PIPN.
Li, Yihang; Pazyra-Murphy, Maria F; Avizonis, Daina; de Sá Tavares Russo, Mariana; Tang, Sophia; Chen, Chiung-Ya; Hsueh, Yi-Ping; Bergholz, Johann S; Jiang, Tao; Zhao, Jean J; Zhu, Jian; Ko, Kwang Woo; Milbrandt, Jeffrey; DiAntonio, Aaron; Segal, Rosalind A.
Afiliação
  • Li Y; Department of Neurobiology, Harvard Medical School, Boston, MA.
  • Pazyra-Murphy MF; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA.
  • Avizonis D; Department of Neurobiology, Harvard Medical School, Boston, MA.
  • de Sá Tavares Russo M; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA.
  • Tang S; Metabolomics Innovation Resource, Goodman Cancer Research Centre, McGill University, Montréal, Quebec, Canada.
  • Chen CY; Metabolomics Innovation Resource, Goodman Cancer Research Centre, McGill University, Montréal, Quebec, Canada.
  • Hsueh YP; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA.
  • Bergholz JS; Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan, Republic of China.
  • Jiang T; Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan, Republic of China.
  • Zhao JJ; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA.
  • Zhu J; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA.
  • Ko KW; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA.
  • Milbrandt J; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA.
  • DiAntonio A; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA.
  • Segal RA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA.
J Cell Biol ; 221(2)2022 02 07.
Article em En | MEDLINE | ID: mdl-34935867
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Axônios / Cálcio / Paclitaxel / Doenças do Sistema Nervoso Periférico / Proteínas do Citoesqueleto / ADP-Ribose Cíclica / Proteínas do Domínio Armadillo / Degeneração Neural Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Axônios / Cálcio / Paclitaxel / Doenças do Sistema Nervoso Periférico / Proteínas do Citoesqueleto / ADP-Ribose Cíclica / Proteínas do Domínio Armadillo / Degeneração Neural Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article