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First-in-human safety, tolerability, and pharmacokinetics of SY-007, a prolonged action neuroprotective drug for ischemic stroke, in healthy Chinese subjects.
Wang, Zhenlei; Jin, Ying; Shen, Qi; Zhuo, Lang; Liu, Runhan; Di, Xiangjie; Xiang, Lisha; Zhang, Guanyu; Wang, Ying; Wang, Yongsheng; Zheng, Li.
Afiliação
  • Wang Z; Clinical Trial Center/NMPA Key Laboratory for Clinical Research and Evaluation of Innovative Drug, West China Hospital of Sichuan University, Chengdu, China.
  • Jin Y; Clinical Trial Center/NMPA Key Laboratory for Clinical Research and Evaluation of Innovative Drug, West China Hospital of Sichuan University, Chengdu, China.
  • Shen Q; Clinical Trial Center/NMPA Key Laboratory for Clinical Research and Evaluation of Innovative Drug, West China Hospital of Sichuan University, Chengdu, China.
  • Zhuo L; Suzhou Yabao Pharmaceutical R&D Co., Ltd., Suzhou, China.
  • Liu R; Clinical Trial Center/NMPA Key Laboratory for Clinical Research and Evaluation of Innovative Drug, West China Hospital of Sichuan University, Chengdu, China.
  • Di X; Clinical Trial Center/NMPA Key Laboratory for Clinical Research and Evaluation of Innovative Drug, West China Hospital of Sichuan University, Chengdu, China.
  • Xiang L; Clinical Trial Center/NMPA Key Laboratory for Clinical Research and Evaluation of Innovative Drug, West China Hospital of Sichuan University, Chengdu, China.
  • Zhang G; Suzhou Yabao Pharmaceutical R&D Co., Ltd., Suzhou, China.
  • Wang Y; Clinical Trial Center/NMPA Key Laboratory for Clinical Research and Evaluation of Innovative Drug, West China Hospital of Sichuan University, Chengdu, China.
  • Wang Y; Clinical Trial Center/NMPA Key Laboratory for Clinical Research and Evaluation of Innovative Drug, West China Hospital of Sichuan University, Chengdu, China.
  • Zheng L; Clinical Trial Center/NMPA Key Laboratory for Clinical Research and Evaluation of Innovative Drug, West China Hospital of Sichuan University, Chengdu, China. Electronic address: zhengli@wchscu.cn.
Eur J Pharm Sci ; 170: 106104, 2022 Mar 01.
Article em En | MEDLINE | ID: mdl-34954052
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Isquemia Encefálica / Fármacos Neuroprotetores / Acidente Vascular Cerebral / AVC Isquêmico Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Animals / Humans País/Região como assunto: Asia Idioma: En Ano de publicação: 2022 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Isquemia Encefálica / Fármacos Neuroprotetores / Acidente Vascular Cerebral / AVC Isquêmico Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Animals / Humans País/Região como assunto: Asia Idioma: En Ano de publicação: 2022 Tipo de documento: Article