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New 2-(2-Phenylethyl)chromone derivatives from agarwood originating from Aquilaria sinensis.
Li, Jun-Tao; Kuang, Tong-Dong; Chen, Hui-Qin; Yang, Li; Wang, Hao; Cai, Cai-Hong; Liu, Shou-Bai; Mei, Wen-Li; Dai, Hao-Fu.
Afiliação
  • Li JT; Hainan Key Laboratory of Research and Development of Natural Product from Li Folk Medicine, Hainan Institute for Tropical Agricultural Resources, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China.
  • Kuang TD; Hainan Key Laboratory of Research and Development of Natural Product from Li Folk Medicine, Hainan Institute for Tropical Agricultural Resources, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China.
  • Chen HQ; Hainan Key Laboratory of Research and Development of Natural Product from Li Folk Medicine, Hainan Institute for Tropical Agricultural Resources, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China.
  • Yang L; Hainan Key Laboratory of Research and Development of Natural Product from Li Folk Medicine, Hainan Institute for Tropical Agricultural Resources, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China.
  • Wang H; Hainan Key Laboratory of Research and Development of Natural Product from Li Folk Medicine, Hainan Institute for Tropical Agricultural Resources, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China.
  • Cai CH; Hainan Key Laboratory of Research and Development of Natural Product from Li Folk Medicine, Hainan Institute for Tropical Agricultural Resources, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China.
  • Liu SB; Key Laboratory of Genetics and Germplasm Enhancement in Tropical Specific Forest Trees and Ornamental Plants, Ministry of Education/Hainan Key Laboratory for Biology of Tropical Specific Ornamental Plants Germplasm, College of Forestry, Hainan University, Haikou 570228, China.
  • Mei WL; Hainan Key Laboratory of Research and Development of Natural Product from Li Folk Medicine, Hainan Institute for Tropical Agricultural Resources, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China.
  • Dai HF; Hainan Key Laboratory of Research and Development of Natural Product from Li Folk Medicine, Hainan Institute for Tropical Agricultural Resources, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China.
J Asian Nat Prod Res ; 24(11): 1033-1040, 2022 Nov.
Article em En | MEDLINE | ID: mdl-34958625
ABSTRACT
Two new dimeric 2-(2-phenylethyl)chromones, aquilasinenones L and M (1 and 2), and one new monomer analogue, 5S, 6 R, 7S, 8 R-tetrahydroxy-[2-(3-methoxy-4-hydroxyphenyl)ethyl]- 5,6,7,8-tetrahydrochromone (3), together with two known compounds, were isolated from the artificial agarwood originating from Aquilaria sinensis. Compound 1 was the first structure found with C8-O-C4"' linkage among 2-(2-phenylethyl)chromone dimers. Their structures were unambiguously elucidated based on 1 D and 2 D NMR spectroscopy, as well as by comparison with the literature. The absolute configuration was determined by ECD calculation. None of the compounds exhibited acetylcholinesterase inhibitory activity.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cromonas / Thymelaeaceae Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cromonas / Thymelaeaceae Idioma: En Ano de publicação: 2022 Tipo de documento: Article