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CAG repeat-binding small molecule improves motor coordination impairment in a mouse model of Dentatorubral-pallidoluysian atrophy.
Hasuike, Yuhei; Tanaka, Hana; Gall-Duncan, Terence; Mehkary, Mustafa; Nakatani, Kazuhiko; Pearson, Christopher E; Tsuji, Shoji; Mochizuki, Hideki; Nakamori, Masayuki.
Afiliação
  • Hasuike Y; Department of Neurology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
  • Tanaka H; Department of Neurology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
  • Gall-Duncan T; Program of Genetics & Genome Biology, The Hospital for Sick Children, The Peter Gilgan Centre for Research and Learning, Toronto, Ontario, Canada.
  • Mehkary M; Program of Genetics & Genome Biology, The Hospital for Sick Children, The Peter Gilgan Centre for Research and Learning, Toronto, Ontario, Canada.
  • Nakatani K; Department of Regulatory Bioorganic Chemistry, The Institute of Scientific and Industrial Research, Osaka University, Osaka, Japan.
  • Pearson CE; Program of Genetics & Genome Biology, The Hospital for Sick Children, The Peter Gilgan Centre for Research and Learning, Toronto, Ontario, Canada.
  • Tsuji S; Department of Molecular Neurology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
  • Mochizuki H; Department of Neurology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
  • Nakamori M; Department of Neurology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan. Electronic address: mnakamor@neurol.med.osaka-u.ac.jp.
Neurobiol Dis ; 163: 105604, 2022 02.
Article em En | MEDLINE | ID: mdl-34968706
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Repetições de Trinucleotídeos / Epilepsias Mioclônicas Progressivas / Destreza Motora / Proteínas do Tecido Nervoso Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Repetições de Trinucleotídeos / Epilepsias Mioclônicas Progressivas / Destreza Motora / Proteínas do Tecido Nervoso Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article