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Integrative gene network and functional analyses identify a prognostically relevant key regulator of metastasis in Ewing sarcoma.
Cidre-Aranaz, Florencia; Li, Jing; Hölting, Tilman L B; Orth, Martin F; Imle, Roland; Kutschmann, Stefanie; Ammirati, Giulia; Ceranski, Katharina; Carreño-Gonzalez, Martha Julia; Kasan, Merve; Marchetto, Aruna; Funk, Cornelius M; Bestvater, Felix; Bersini, Simone; Arrigoni, Chiara; Moretti, Matteo; Thiel, Uwe; Baumhoer, Daniel; Sahm, Felix; Pfister, Stefan M; Hartmann, Wolfgang; Dirksen, Uta; Romero-Pérez, Laura; Banito, Ana; Ohmura, Shunya; Musa, Julian; Kirchner, Thomas; Knott, Maximilian M L; Grünewald, Thomas G P.
Afiliação
  • Cidre-Aranaz F; Hopp-Children's Cancer Center (KiTZ), Heidelberg, Germany.
  • Li J; Division of Translational Pediatric Sarcoma Research (B410), German Cancer Research Center (DKFZ), German Cancer Consortium (DKTK), Im Neuenheimer Feld 280, 69210, Heidelberg, Germany.
  • Hölting TLB; Hopp-Children's Cancer Center (KiTZ), Heidelberg, Germany.
  • Orth MF; Division of Translational Pediatric Sarcoma Research (B410), German Cancer Research Center (DKFZ), German Cancer Consortium (DKTK), Im Neuenheimer Feld 280, 69210, Heidelberg, Germany.
  • Imle R; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
  • Kutschmann S; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
  • Ammirati G; Hopp-Children's Cancer Center (KiTZ), Heidelberg, Germany.
  • Ceranski K; Soft-Tissue Sarcoma Junior Research Group, German Cancer Research Center (DKFZ), German Cancer Consortium (DKTK), Heidelberg, Germany.
  • Carreño-Gonzalez MJ; Faculty of Biosciences, Heidelberg University, Heidelberg, Germany.
  • Kasan M; Division of Pediatric Surgery, Department of General, Visceral and Transplantation Surgery, University Hospital Heidelberg, Heidelberg, Germany.
  • Marchetto A; Hopp-Children's Cancer Center (KiTZ), Heidelberg, Germany.
  • Funk CM; Division of Translational Pediatric Sarcoma Research (B410), German Cancer Research Center (DKFZ), German Cancer Consortium (DKTK), Im Neuenheimer Feld 280, 69210, Heidelberg, Germany.
  • Bestvater F; Regenerative Medicine Technologies Laboratory, Ente Ospedaliero Cantonale (EOC), Lugano, Switzerland.
  • Bersini S; Hopp-Children's Cancer Center (KiTZ), Heidelberg, Germany.
  • Arrigoni C; Division of Translational Pediatric Sarcoma Research (B410), German Cancer Research Center (DKFZ), German Cancer Consortium (DKTK), Im Neuenheimer Feld 280, 69210, Heidelberg, Germany.
  • Moretti M; Hopp-Children's Cancer Center (KiTZ), Heidelberg, Germany.
  • Thiel U; Division of Translational Pediatric Sarcoma Research (B410), German Cancer Research Center (DKFZ), German Cancer Consortium (DKTK), Im Neuenheimer Feld 280, 69210, Heidelberg, Germany.
  • Baumhoer D; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
  • Sahm F; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
  • Pfister SM; Hopp-Children's Cancer Center (KiTZ), Heidelberg, Germany.
  • Hartmann W; Division of Translational Pediatric Sarcoma Research (B410), German Cancer Research Center (DKFZ), German Cancer Consortium (DKTK), Im Neuenheimer Feld 280, 69210, Heidelberg, Germany.
  • Dirksen U; Light Microscopy Facility (W210), German Cancer Research Center (DKFZ), German Cancer Consortium (DKTK), Heidelberg, Germany.
  • Romero-Pérez L; Regenerative Medicine Technologies Laboratory, Ente Ospedaliero Cantonale (EOC), Lugano, Switzerland.
  • Banito A; Regenerative Medicine Technologies Laboratory, Ente Ospedaliero Cantonale (EOC), Lugano, Switzerland.
  • Ohmura S; Regenerative Medicine Technologies Laboratory, Ente Ospedaliero Cantonale (EOC), Lugano, Switzerland.
  • Musa J; Biomedical Sciences Faculty, Università della Svizzera Italiana (USI), Lugano, Switzerland.
  • Kirchner T; Technical University of Munich, School of Medicine, Department of Pediatrics and Children's Cancer Research Center, Munich, Germany.
  • Knott MML; Bone Tumor Reference Center, Institute of Pathology of the University Hospital of Basel, Basel, Switzerland.
  • Grünewald TGP; Hopp-Children's Cancer Center (KiTZ), Heidelberg, Germany.
Mol Cancer ; 21(1): 1, 2022 01 03.
Article em En | MEDLINE | ID: mdl-34980141
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sarcoma de Ewing / Neoplasias Ósseas / Biomarcadores Tumorais / Regulação Neoplásica da Expressão Gênica / Redes Reguladoras de Genes Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sarcoma de Ewing / Neoplasias Ósseas / Biomarcadores Tumorais / Regulação Neoplásica da Expressão Gênica / Redes Reguladoras de Genes Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article