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Fluctuating methylation clocks for cell lineage tracing at high temporal resolution in human tissues.
Gabbutt, Calum; Schenck, Ryan O; Weisenberger, Daniel J; Kimberley, Christopher; Berner, Alison; Househam, Jacob; Lakatos, Eszter; Robertson-Tessi, Mark; Martin, Isabel; Patel, Roshani; Clark, Susan K; Latchford, Andrew; Barnes, Chris P; Leedham, Simon J; Anderson, Alexander R A; Graham, Trevor A; Shibata, Darryl.
Afiliação
  • Gabbutt C; Evolution and Cancer Laboratory, Centre for Genomics and Computational Biology, Barts Cancer Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
  • Schenck RO; Department of Cell and Developmental Biology, University College London, London, UK.
  • Weisenberger DJ; London Interdisciplinary Doctoral Training Programme (LIDo), London, UK.
  • Kimberley C; Integrated Mathematical Oncology Department, Moffitt Cancer Center, Tampa, FL, USA.
  • Berner A; Intestinal Stem Cell Biology Lab, Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.
  • Househam J; Department of Biochemistry and Molecular Medicine, University of Southern California, Los Angeles, CA, USA.
  • Lakatos E; Evolution and Cancer Laboratory, Centre for Genomics and Computational Biology, Barts Cancer Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
  • Robertson-Tessi M; Evolution and Cancer Laboratory, Centre for Genomics and Computational Biology, Barts Cancer Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
  • Martin I; Evolution and Cancer Laboratory, Centre for Genomics and Computational Biology, Barts Cancer Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
  • Patel R; Evolution and Cancer Laboratory, Centre for Genomics and Computational Biology, Barts Cancer Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
  • Clark SK; Integrated Mathematical Oncology Department, Moffitt Cancer Center, Tampa, FL, USA.
  • Latchford A; Evolution and Cancer Laboratory, Centre for Genomics and Computational Biology, Barts Cancer Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
  • Barnes CP; St. Mark's Hospital, Harrow, London, UK.
  • Leedham SJ; Evolution and Cancer Laboratory, Centre for Genomics and Computational Biology, Barts Cancer Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
  • Anderson ARA; St. Mark's Hospital, Harrow, London, UK.
  • Graham TA; St. Mark's Hospital, Harrow, London, UK.
  • Shibata D; Department of Surgery and Cancer, Imperial College, London, UK.
Nat Biotechnol ; 40(5): 720-730, 2022 05.
Article em En | MEDLINE | ID: mdl-34980912

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Metilação de DNA / Células-Tronco Adultas Limite: Adult / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Metilação de DNA / Células-Tronco Adultas Limite: Adult / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article