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Analysis of antibodies from HCV elite neutralizers identifies genetic determinants of broad neutralization.
Weber, Timm; Potthoff, Julian; Bizu, Sven; Labuhn, Maurice; Dold, Leona; Schoofs, Till; Horning, Marcel; Ercanoglu, Meryem S; Kreer, Christoph; Gieselmann, Lutz; Vanshylla, Kanika; Langhans, Bettina; Janicki, Hanna; Ströh, Luisa J; Knops, Elena; Nierhoff, Dirk; Spengler, Ulrich; Kaiser, Rolf; Bjorkman, Pamela J; Krey, Thomas; Bankwitz, Dorothea; Pfeifer, Nico; Pietschmann, Thomas; Flyak, Andrew I; Klein, Florian.
Afiliação
  • Weber T; Laboratory of Experimental Immunology, Institute of Virology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.
  • Potthoff J; Laboratory of Experimental Immunology, Institute of Virology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.
  • Bizu S; Methods in Medical Informatics, Department of Computer Science, University of Tübingen, 72076 Tübingen, Germany.
  • Labuhn M; Twincore, Centre for Experimental and Clinical Infection Research, Institute of Experimental Virology, 30625 Hannover, Germany.
  • Dold L; Laboratory of Experimental Immunology, Institute of Virology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany; Department of Internal Medicine I, University Hospital of Bonn, 53127 Bonn, Germany; German Center for Infection Research (DZIF), Partner
  • Schoofs T; Laboratory of Experimental Immunology, Institute of Virology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.
  • Horning M; Laboratory of Experimental Immunology, Institute of Virology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.
  • Ercanoglu MS; Laboratory of Experimental Immunology, Institute of Virology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.
  • Kreer C; Laboratory of Experimental Immunology, Institute of Virology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.
  • Gieselmann L; Laboratory of Experimental Immunology, Institute of Virology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany; German Center for Infection Research (DZIF), Partner Site Bonn-Cologne, 50931 Cologne, Germany.
  • Vanshylla K; Laboratory of Experimental Immunology, Institute of Virology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.
  • Langhans B; Department of Internal Medicine I, University Hospital of Bonn, 53127 Bonn, Germany; German Center for Infection Research (DZIF), Partner Site Bonn-Cologne, 50931 Cologne, Germany.
  • Janicki H; Laboratory of Experimental Immunology, Institute of Virology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.
  • Ströh LJ; Institute of Virology, Hannover Medical School, 30625 Hannover, Germany.
  • Knops E; Institute of Virology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.
  • Nierhoff D; Department of Gastroenterology and Hepatology, Faculty of Medicine and University Hospital Cologne, 50931 Cologne, Germany.
  • Spengler U; Department of Internal Medicine I, University Hospital of Bonn, 53127 Bonn, Germany; German Center for Infection Research (DZIF), Partner Site Bonn-Cologne, 50931 Cologne, Germany.
  • Kaiser R; German Center for Infection Research (DZIF), Partner Site Bonn-Cologne, 50931 Cologne, Germany; Institute of Virology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.
  • Bjorkman PJ; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
  • Krey T; Institute of Virology, Hannover Medical School, 30625 Hannover, Germany; Center of Structural and Cell Biology in Medicine, Institute of Biochemistry, University of Lübeck, 23562 Luebeck, Germany; Centre for Structural Systems Biology (CSSB), 22607 Hamburg, Germany; German Center for Infection Resea
  • Bankwitz D; Twincore, Centre for Experimental and Clinical Infection Research, Institute of Experimental Virology, 30625 Hannover, Germany.
  • Pfeifer N; Methods in Medical Informatics, Department of Computer Science, University of Tübingen, 72076 Tübingen, Germany.
  • Pietschmann T; Twincore, Centre for Experimental and Clinical Infection Research, Institute of Experimental Virology, 30625 Hannover, Germany; Cluster of Excellence RESIST (EXC 2155), Hannover Medical School, 30625 Hannover, Germany; German Center for Infection Research (DZIF), Partner Site Hannover-Braunschweig,
  • Flyak AI; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
  • Klein F; Laboratory of Experimental Immunology, Institute of Virology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany; German Center for Infection Research (DZIF), Partner Site Bonn-Cologne, 50931 Cologne, Germany; Institute of Virology, Faculty of Medicine
Immunity ; 55(2): 341-354.e7, 2022 02 08.
Article em En | MEDLINE | ID: mdl-34990590
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hepacivirus / Anticorpos Anti-Hepatite C / Anticorpos Amplamente Neutralizantes Tipo de estudo: Prognostic_studies Limite: Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hepacivirus / Anticorpos Anti-Hepatite C / Anticorpos Amplamente Neutralizantes Tipo de estudo: Prognostic_studies Limite: Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2022 Tipo de documento: Article