The functional variant in promoter of OVCA1 was associated with the risk of gastric cancer in the northeast Chinese Han population.

Yu, Lina; Li, Yunlong; Wang, Hui; Wang, Dong; Hao, Huiting; Zhang, DongWei; Liang, Xiao; Cai, Mengdi; Guan, Rongwei; Bai, Jing; Yu, Jingcui

Yu, Lina; Li, Yunlong; Wang, Hui; Wang, Dong; Hao, Huiting; Zhang, DongWei; Liang, Xiao; Cai, Mengdi; Guan, Rongwei; Bai, Jing; Yu, Jingcui.

Afiliação

Yu L; Scientific Research Centre, The Second Affiliated Hospital of Harbin Medical University, Harbin 150081, China.
Li Y; Department of General Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin 150081, China.
Wang H; Scientific Research Centre, The Second Affiliated Hospital of Harbin Medical University, Harbin 150081, China.
Wang D; Scientific Research Centre, The Second Affiliated Hospital of Harbin Medical University, Harbin 150081, China.
Hao H; Scientific Research Centre, The Second Affiliated Hospital of Harbin Medical University, Harbin 150081, China; Clinical Laboratory, Harbin Medical University Cancer Hospital, Harbin 150081, China.
Zhang D; Scientific Research Centre, The Second Affiliated Hospital of Harbin Medical University, Harbin 150081, China; Clinical Laboratory, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China.
Liang X; Key Laboratory of Preservation of Human Genetic Resources and Disease Control in China (Harbin Medical University), Ministry of Education, Harbin 150081, China.
Cai M; Key Laboratory of Preservation of Human Genetic Resources and Disease Control in China (Harbin Medical University), Ministry of Education, Harbin 150081, China.
Guan R; Key Laboratory of Preservation of Human Genetic Resources and Disease Control in China (Harbin Medical University), Ministry of Education, Harbin 150081, China.
Bai J; Key Laboratory of Preservation of Human Genetic Resources and Disease Control in China (Harbin Medical University), Ministry of Education, Harbin 150081, China.
Yu J; Scientific Research Centre, The Second Affiliated Hospital of Harbin Medical University, Harbin 150081, China; Key Laboratory of Preservation of Human Genetic Resources and Disease Control in China (Harbin Medical University), Ministry of Education, Harbin 150081, China. Electronic address: yujingcu

Pathol Res Pract ; 230: 153755, 2022 Feb.

Article em En | MEDLINE | ID: mdl-34990869

Assuntos

Biomarcadores Tumorais/genética; Antígenos de Histocompatibilidade Menor/genética; Polimorfismo de Nucleotídeo Único; Regiões Promotoras Genéticas; Neoplasias Gástricas/genética; Proteínas Supressoras de Tumor/genética; Subunidades do Complexo de Proteínas Adaptadoras/genética; Subunidades do Complexo de Proteínas Adaptadoras/metabolismo; Idoso; Povo Asiático/genética; Biomarcadores Tumorais/metabolismo; Estudos de Casos e Controles; China/epidemiologia; Feminino; Estudos de Associação Genética; Predisposição Genética para Doença; Células HEK293; Humanos; Masculino; Pessoa de Meia-Idade; Antígenos de Histocompatibilidade Menor/metabolismo; Fenótipo; Medição de Risco; Fatores de Risco; Neoplasias Gástricas/etnologia; Neoplasias Gástricas/metabolismo; Neoplasias Gástricas/patologia; Carga Tumoral; Proteínas Supressoras de Tumor/metabolismo

Palavras-chave

Gastric cancer; OVCA1; Single nucleotide polymorphism; Susceptibility

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Gástricas / Biomarcadores Tumorais / Antígenos de Histocompatibilidade Menor / Regiões Promotoras Genéticas / Polimorfismo de Nucleotídeo Único / Proteínas Supressoras de Tumor Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Female / Humans / Male / Middle aged País/Região como assunto: Asia Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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