Geraniin inhibits whole blood IFN-Î³ and IL-6 and promotes IL-1ß and IL-8, and stimulates calcium-dependent and sucrose-sensitive erythrocyte death.

Alsughayyir, Jawaher; Alshaiddi, Wafa; Alsubki, Roua; Alshammary, Amal; Basudan, Ahmed M; Alfhili, Mohammad A

Alsughayyir, Jawaher; Alshaiddi, Wafa; Alsubki, Roua; Alshammary, Amal; Basudan, Ahmed M; Alfhili, Mohammad A.

Afiliação

Alsughayyir J; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Saud University, Riyadh 12372, Saudi Arabia.
Alshaiddi W; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Saud University, Riyadh 12372, Saudi Arabia.
Alsubki R; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Saud University, Riyadh 12372, Saudi Arabia.
Alshammary A; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Saud University, Riyadh 12372, Saudi Arabia.
Basudan AM; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Saud University, Riyadh 12372, Saudi Arabia.
Alfhili MA; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Saud University, Riyadh 12372, Saudi Arabia. Electronic address: malfeehily@ksu.edu.sa.

Toxicol Appl Pharmacol ; 436: 115881, 2022 02 01.

Article em En | MEDLINE | ID: mdl-35026210

Assuntos

Cálcio/metabolismo; Morte Celular/efeitos dos fármacos; Citocinas/metabolismo; Eritrócitos/efeitos dos fármacos; Eritrócitos/metabolismo; Glucosídeos/farmacologia; Taninos Hidrolisáveis/farmacologia; Sacarose/metabolismo; Eriptose/efeitos dos fármacos; Hemólise/efeitos dos fármacos; Humanos; Interferon gama/metabolismo; Interleucina-10/metabolismo; Interleucina-1beta/metabolismo; Interleucina-6/metabolismo; Interleucina-8/metabolismo; Fator de Necrose Tumoral alfa/metabolismo

Palavras-chave

Calcium; Cytokine; Eryptosis; Geraniin; Hemolysis; Whole blood

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sacarose / Cálcio / Citocinas / Morte Celular / Taninos Hidrolisáveis / Eritrócitos / Glucosídeos Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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