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Novel microtubule inhibitor SQ overcomes multidrug resistance in MCF-7/ADR cells by inhibiting BCRP function and mediating apoptosis.
Chang, Xing; Liu, Zi; Cao, Simeng; Bian, Jiang; Zheng, Dayong; Wang, Nuo; Guan, Qi; Wu, Yingliang; Zhang, Weige; Li, Zengqiang; Zuo, Daiying.
Afiliação
  • Chang X; Department of Pharmacology, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang 110016, China.
  • Liu Z; Department of Pharmacology, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang 110016, China.
  • Cao S; Department of Pharmacology, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang 110016, China.
  • Bian J; Department of Pharmacology, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang 110016, China.
  • Zheng D; Department of Pharmacology, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang 110016, China; School of Pharmacy, North China University of Science and Technology, 21 Bohai Road, Caofeidian District, Tangshan 063210, China.
  • Wang N; Department of Pharmacology, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang 110016, China.
  • Guan Q; Key Laboratory of Structure-Based Drug Design and Discovery, Ministry of Education, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang 110016, China.
  • Wu Y; Department of Pharmacology, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang 110016, China.
  • Zhang W; Key Laboratory of Structure-Based Drug Design and Discovery, Ministry of Education, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang 110016, China. Electronic address: zhangweige2000@sina.com.
  • Li Z; Department of Pharmacology, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang 110016, China. Electronic address: q8v@foxmail.com.
  • Zuo D; Department of Pharmacology, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang 110016, China. Electronic address: zuodaiying@163.com.
Toxicol Appl Pharmacol ; 436: 115883, 2022 02 01.
Article em En | MEDLINE | ID: mdl-35031325
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Compostos Organosselênicos / Apoptose / Resistência a Múltiplos Medicamentos / Resistencia a Medicamentos Antineoplásicos / Moduladores de Tubulina / Membro 2 da Subfamília G de Transportadores de Cassetes de Ligação de ATP / Microtúbulos / Proteínas de Neoplasias Limite: Female / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Compostos Organosselênicos / Apoptose / Resistência a Múltiplos Medicamentos / Resistencia a Medicamentos Antineoplásicos / Moduladores de Tubulina / Membro 2 da Subfamília G de Transportadores de Cassetes de Ligação de ATP / Microtúbulos / Proteínas de Neoplasias Limite: Female / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article