Lipotoxicity Downstream of &#945;-Synuclein Imbalance: A Relevant Pathomechanism in Synucleinopathies?

Tripathi, Arati; Fanning, Saranna; Dettmer, Ulf

Lipotoxicity Downstream of α-Synuclein Imbalance: A Relevant Pathomechanism in Synucleinopathies?

Tripathi, Arati; Fanning, Saranna; Dettmer, Ulf.

Afiliação

Tripathi A; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Fanning S; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Dettmer U; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

Biomolecules ; 12(1)2021 12 28.

Article em En | MEDLINE | ID: mdl-35053188

Assuntos

Doença de Gaucher; Doença de Parkinson; Sinucleinopatias; Doença de Gaucher/patologia; Humanos; Neurônios/metabolismo; Doença de Parkinson/metabolismo; alfa-Sinucleína/metabolismo

Palavras-chave

Lewy body dementia; Parkinson's disease; alpha-synuclein; lipidopathy; lipids; neurotoxicity; stearoyl-CoA desaturase

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Doença de Gaucher / Sinucleinopatias Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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