Isoproterenol, an adrenergic ß receptor agonist, induces metallothionein synthesis followed by canceling amyloid ß<sub>1-42</sub>-induced neurodegeneration.

Kawano, Yuya; Tamura, Kotaro; Egawa, Mako; Tamano, Haruna; Takeda, Atsushi

Isoproterenol, an adrenergic ß receptor agonist, induces metallothionein synthesis followed by canceling amyloid ß_1-42-induced neurodegeneration.

Kawano, Yuya; Tamura, Kotaro; Egawa, Mako; Tamano, Haruna; Takeda, Atsushi.

Afiliação

Kawano Y; School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan.
Tamura K; School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan.
Egawa M; School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan.
Tamano H; School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan.
Takeda A; School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan. takedaa@u-shizuoka-ken.ac.jp.

Biometals ; 35(2): 303-312, 2022 04.

Article em En | MEDLINE | ID: mdl-35064350

Assuntos

Peptídeos beta-Amiloides; Metalotioneína; Agonistas Adrenérgicos beta/farmacologia; Animais; Isoproterenol/farmacologia; Camundongos; Fragmentos de Peptídeos/farmacologia; Zinco/metabolismo; Zinco/farmacologia

Palavras-chave

Adrenergic ß receptor; Alzheimer's disease; Amyloid ß1-42; Isoproterenol; Metallothionein; Zn2+ dysregulation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos beta-Amiloides / Metalotioneína Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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