T and NK cell lymphoma cell lines do not rely on ZAP-70 for survival.

de Mel, Sanjay; Mustafa, Nurulhuda; Selvarajan, Viknesvaran; Azaman, Muhammad Irfan; Jaynes, Patrick William; Venguidessane, Shruthi; Phuong, Hoang Mai; Alnaseri, Zubaida Talal; Phyu, The; Girard, Louis-Pierre; Chng, Wee Joo; Wardyn, Joanna; Li, Ying; An, Omer; Yang, Henry; Ng, Siok Bian; Jeyasekharan, Anand D

de Mel, Sanjay; Mustafa, Nurulhuda; Selvarajan, Viknesvaran; Azaman, Muhammad Irfan; Jaynes, Patrick William; Venguidessane, Shruthi; Phuong, Hoang Mai; Alnaseri, Zubaida Talal; Phyu, The; Girard, Louis-Pierre; Chng, Wee Joo; Wardyn, Joanna; Li, Ying; An, Omer; Yang, Henry; Ng, Siok Bian; Jeyasekharan, Anand D.

Afiliação

de Mel S; Department of Haematology Oncology, National University Cancer Institute Singapore, National University Health System Singapore, Singapore, Singapore.
Mustafa N; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Selvarajan V; Department of Pathology Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Azaman MI; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.
Jaynes PW; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.
Venguidessane S; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.
Phuong HM; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.
Alnaseri ZT; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.
Phyu T; Department of Pathology Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Girard LP; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.
Chng WJ; School of Medicine, University of Aberdeen, Aberdeen, United Kingdom.
Wardyn J; Aberdeen Royal Infirmary, NHS Grampian, Scotland, United Kingdom.
Li Y; Department of Haematology Oncology, National University Cancer Institute Singapore, National University Health System Singapore, Singapore, Singapore.
An O; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Yang H; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.
Ng SB; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.
Jeyasekharan AD; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.

PLoS One ; 17(1): e0261469, 2022.

Article em En | MEDLINE | ID: mdl-35077445

Assuntos

Gefitinibe/farmacologia; Linfoma Extranodal de Células T-NK/metabolismo; Linfoma de Células T Periférico/metabolismo; Regulação para Cima; Proteína-Tirosina Quinase ZAP-70/metabolismo; Linhagem Celular Tumoral; Proliferação de Células/efeitos dos fármacos; Sobrevivência Celular/efeitos dos fármacos; Regulação Neoplásica da Expressão Gênica; Técnicas de Silenciamento de Genes; Humanos; Células Jurkat; Linfoma Extranodal de Células T-NK/genética; Linfoma de Células T Periférico/genética; Fosforilação/efeitos dos fármacos; Transdução de Sinais/efeitos dos fármacos; Proteína-Tirosina Quinase ZAP-70/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Regulação para Cima / Linfoma de Células T Periférico / Proteína-Tirosina Quinase ZAP-70 / Linfoma Extranodal de Células T-NK / Gefitinibe Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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