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TGF-ß-activated kinase-1 inhibitor LL-Z1640-2 reduces joint inflammation and bone destruction in mouse models of rheumatoid arthritis by inhibiting NLRP3 inflammasome, TACE, TNF-α and RANKL expression.
Tenshin, Hirofumi; Teramachi, Jumpei; Ashtar, Mohannad; Hiasa, Masahiro; Inoue, Yusuke; Oda, Asuka; Tanimoto, Kotaro; Shimizu, So; Higa, Yoshiki; Harada, Takeshi; Oura, Masahiro; Sogabe, Kimiko; Hara, Tomoyo; Sumitani, Ryohei; Maruhashi, Tomoko; Sebe, Mayu; Tsutsumi, Rie; Sakaue, Hiroshi; Endo, Itsuro; Matsumoto, Toshio; Tanaka, Eiji; Abe, Masahiro.
Afiliação
  • Tenshin H; Department of Orthodontics and Dentofacial Orthopedics Tokushima University Graduate School of Biomedical Sciences Tokushima Japan.
  • Teramachi J; Department of Hematology, Endocrinology and Metabolism Tokushima University Graduate School of Biomedical Sciences Tokushima Japan.
  • Ashtar M; Department of Oral Function and Anatomy, Graduate School of Medicine Dentistry and Pharmaceutical Sciences Okayama University Okayama Japan.
  • Hiasa M; Department of Orthodontics and Dentofacial Orthopedics Tokushima University Graduate School of Biomedical Sciences Tokushima Japan.
  • Inoue Y; Department of Orthodontics and Dentofacial Orthopedics Tokushima University Graduate School of Biomedical Sciences Tokushima Japan.
  • Oda A; Department of Hematology, Endocrinology and Metabolism Tokushima University Graduate School of Biomedical Sciences Tokushima Japan.
  • Tanimoto K; Department of Hematology, Endocrinology and Metabolism Tokushima University Graduate School of Biomedical Sciences Tokushima Japan.
  • Shimizu S; Department of Orthodontics and Dentofacial Orthopedics Tokushima University Graduate School of Biomedical Sciences Tokushima Japan.
  • Higa Y; Department of Orthodontics and Dentofacial Orthopedics Tokushima University Graduate School of Biomedical Sciences Tokushima Japan.
  • Harada T; Department of Orthodontics and Dentofacial Orthopedics Tokushima University Graduate School of Biomedical Sciences Tokushima Japan.
  • Oura M; Department of Hematology, Endocrinology and Metabolism Tokushima University Graduate School of Biomedical Sciences Tokushima Japan.
  • Sogabe K; Department of Hematology, Endocrinology and Metabolism Tokushima University Graduate School of Biomedical Sciences Tokushima Japan.
  • Hara T; Department of Hematology, Endocrinology and Metabolism Tokushima University Graduate School of Biomedical Sciences Tokushima Japan.
  • Sumitani R; Department of Hematology, Endocrinology and Metabolism Tokushima University Graduate School of Biomedical Sciences Tokushima Japan.
  • Maruhashi T; Department of Hematology, Endocrinology and Metabolism Tokushima University Graduate School of Biomedical Sciences Tokushima Japan.
  • Sebe M; Department of Hematology, Endocrinology and Metabolism Tokushima University Graduate School of Biomedical Sciences Tokushima Japan.
  • Tsutsumi R; Department of Nutrition and Metabolism Tokushima University Graduate School of Biomedical Sciences Tokushima Japan.
  • Sakaue H; Department of Nutrition and Metabolism Tokushima University Graduate School of Biomedical Sciences Tokushima Japan.
  • Endo I; Department of Nutrition and Metabolism Tokushima University Graduate School of Biomedical Sciences Tokushima Japan.
  • Matsumoto T; Department of Bioregulatory Sciences Tokushima University Graduate School of Biomedical Sciences Tokushima Japan.
  • Tanaka E; Fujii Memorial Institute of Medical Sciences Tokushima University Tokushima Japan.
  • Abe M; Department of Orthodontics and Dentofacial Orthopedics Tokushima University Graduate School of Biomedical Sciences Tokushima Japan.
Clin Transl Immunology ; 11(1): e1371, 2022.
Article em En | MEDLINE | ID: mdl-35079379
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article