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A highly selective 2''-O-glycosyltransferase from Ziziphus jujuba and De novo biosynthesis of isovitexin 2''-O-glucoside.
Zhang, Ya-Qun; Wang, Zi-Long; Chen, Zhuo; Jin, Zheng-Tong; Hasan, Aobulikasimu; Wang, Hai-Dong; Sun, Yu-Wei; Qiao, Xue; Wang, Yong; Ye, Min.
Afiliação
  • Zhang YQ; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 38 Xueyuan Road, Beijing 100191, China. qiaoxue@bjmu.edu.cn.
  • Wang ZL; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 38 Xueyuan Road, Beijing 100191, China. qiaoxue@bjmu.edu.cn.
  • Chen Z; CAS-Key Laboratory of Synthetic Biology, CAS Center for Excellence in Molecular Plant Sciences, Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai 200032, China. yongwang@cemps.ac.cn.
  • Jin ZT; University of Chinese Academy of Sciences, Beijing 100039, China.
  • Hasan A; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 38 Xueyuan Road, Beijing 100191, China. qiaoxue@bjmu.edu.cn.
  • Wang HD; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 38 Xueyuan Road, Beijing 100191, China. qiaoxue@bjmu.edu.cn.
  • Sun YW; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 38 Xueyuan Road, Beijing 100191, China. qiaoxue@bjmu.edu.cn.
  • Qiao X; CAS-Key Laboratory of Synthetic Biology, CAS Center for Excellence in Molecular Plant Sciences, Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai 200032, China. yongwang@cemps.ac.cn.
  • Wang Y; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 38 Xueyuan Road, Beijing 100191, China. qiaoxue@bjmu.edu.cn.
  • Ye M; CAS-Key Laboratory of Synthetic Biology, CAS Center for Excellence in Molecular Plant Sciences, Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai 200032, China. yongwang@cemps.ac.cn.
Chem Commun (Camb) ; 58(15): 2472-2475, 2022 Feb 17.
Article em En | MEDLINE | ID: mdl-35084410
ABSTRACT
A novel and efficient 2''-O-glycosyltransferase ZjOGT38 was identified from Ziziphus jujuba. It could regio-selectively glycosylate 2-hydroxyflavanone C-glycosides. ZjOGT38 allowed de novo biosynthesis of isovitexin 2''-O-glucoside in E. coli.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glicosiltransferases / Ziziphus / Glucosídeos / Isoflavonas Idioma: En Ano de publicação: 2022 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glicosiltransferases / Ziziphus / Glucosídeos / Isoflavonas Idioma: En Ano de publicação: 2022 Tipo de documento: Article