Cetylpyridinium chloride promotes disaggregation of SARS-CoV-2 virus-like particles.
J Oral Microbiol
; 14(1): 2030094, 2022.
Article
em En
| MEDLINE
| ID: mdl-35087641
ABSTRACT
BACKGROUND:
SARS-CoV-2 is continuously disseminating worldwide. The development of strategies to break transmission is mandatory. AIM OF THE STUDY To investigate the potential of cetylpyridinium chloride (CPC) as a viral inhibitor.METHODS:
SARS-CoV-2 Virus Like-Particles (VLPs) were incubated with CPC, a potent surfactant routinely included in mouthwash preparations.RESULTS:
Concentrations of 0.05% CPC (w/v) commonly used in mouthwash preparations are sufficient to promote the rupture of SARS-CoV-2 VLP membranes.CONCLUSION:
Including CPC in mouthwashes could be a prophylactic strategy to keep SARS-CoV-2 from spreading.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article