From organ-on-chip to body-on-chip: The next generation of microfluidics platforms for in vitro drug efficacy and toxicity testing.

Lacombe, Jerome; Soldevila, Maria; Zenhausern, Frederic

Lacombe, Jerome; Soldevila, Maria; Zenhausern, Frederic.

Afiliação

Lacombe J; Center for Applied Nanobioscience and Medicine, Phoenix, AZ, United States; Department of Basic Medical Sciences, College of Medicine-Phoenix, The University of Arizona, Phoenix, AZ, United States. Electronic address: jlacombe@email.arizona.edu.
Soldevila M; Center for Applied Nanobioscience and Medicine, Phoenix, AZ, United States.
Zenhausern F; Center for Applied Nanobioscience and Medicine, Phoenix, AZ, United States; Department of Basic Medical Sciences, College of Medicine-Phoenix, The University of Arizona, Phoenix, AZ, United States. Electronic address: fzenhaus@email.arizona.edu.

Prog Mol Biol Transl Sci ; 187(1): 41-91, 2022.

Article em En | MEDLINE | ID: mdl-35094781

Assuntos

Dispositivos Lab-On-A-Chip; Microfluídica; Desenvolvimento de Medicamentos; Avaliação Pré-Clínica de Medicamentos; Humanos; Testes de Toxicidade

Palavras-chave

ADME process; Body-on-chip; Drug development; Microfluidics; Microphysiological systems; Organ-on-chip; Toxicity

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Microfluídica / Dispositivos Lab-On-A-Chip Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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