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Aberrant stromal tissue factor localisation and mycolactone-driven vascular dysfunction, exacerbated by IL-1ß, are linked to fibrin formation in Buruli ulcer lesions.
Hsieh, Louise Tzung-Harn; Dos Santos, Scott J; Hall, Belinda S; Ogbechi, Joy; Loglo, Aloysius D; Salguero, Francisco Javier; Ruf, Marie-Thérèse; Pluschke, Gerd; Simmonds, Rachel E.
Afiliação
  • Hsieh LT; Department of Microbial Sciences, School of Bioscience and Medicine, University of Surrey, Guildford, United Kingdom.
  • Dos Santos SJ; Department of Microbial Sciences, School of Bioscience and Medicine, University of Surrey, Guildford, United Kingdom.
  • Hall BS; Department of Microbial Sciences, School of Bioscience and Medicine, University of Surrey, Guildford, United Kingdom.
  • Ogbechi J; Department of Microbial Sciences, School of Bioscience and Medicine, University of Surrey, Guildford, United Kingdom.
  • Loglo AD; Department of Microbial Sciences, School of Bioscience and Medicine, University of Surrey, Guildford, United Kingdom.
  • Salguero FJ; UK Health Security Agency, Manor Farm Road, Porton Down, Salisbury, United Kingdom.
  • Ruf MT; Swiss Tropical and Public Health Institute, Basel, Switzerland.
  • Pluschke G; University of Basel, Basel, Switzerland.
  • Simmonds RE; Swiss Tropical and Public Health Institute, Basel, Switzerland.
PLoS Pathog ; 18(1): e1010280, 2022 01.
Article em En | MEDLINE | ID: mdl-35100311
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pele / Tromboplastina / Fibrina / Macrolídeos / Mycobacterium ulcerans / Interleucina-1beta / Úlcera de Buruli / Células Endoteliais da Veia Umbilical Humana Tipo de estudo: Clinical_trials Limite: Adolescent / Adult / Aged / Child / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pele / Tromboplastina / Fibrina / Macrolídeos / Mycobacterium ulcerans / Interleucina-1beta / Úlcera de Buruli / Células Endoteliais da Veia Umbilical Humana Tipo de estudo: Clinical_trials Limite: Adolescent / Adult / Aged / Child / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2022 Tipo de documento: Article