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Endovascular treatment for acute basilar artery occlusion: A multicenter randomized controlled trial (ATTENTION).
Tao, Chunrong; Li, Rui; Zhu, Yuyou; Qun, Sen; Xu, Pengfei; Wang, Li; Zhang, Chao; Liu, Tianlong; Song, Jianlong; Sun, Wen; Wang, Guoping; Baxter, Blaise; Qureshi, Adnan; Liu, Xinfeng; Nogueira, Raul G; Hu, Wei.
Afiliação
  • Tao C; Stroke Center and Department of Neurology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
  • Li R; Stroke Center and Department of Neurology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
  • Zhu Y; Stroke Center and Department of Neurology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
  • Qun S; Stroke Center and Department of Neurology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
  • Xu P; Stroke Center and Department of Neurology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
  • Wang L; Stroke Center and Department of Neurology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
  • Zhang C; Stroke Center and Department of Neurology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
  • Liu T; Stroke Center and Department of Neurology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
  • Song J; Stroke Center and Department of Neurology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
  • Sun W; Stroke Center and Department of Neurology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
  • Wang G; Stroke Center and Department of Neurology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
  • Baxter B; Lehigh Valley Health Network, Allentown, PA, USA.
  • Qureshi A; Zeenat Qureshi Stroke Research Center, University of Minnesota-Morris, Morris, MN, USA.
  • Liu X; Stroke Center and Department of Neurology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
  • Nogueira RG; Department of Neurology, Affiliated Jinling Hospital, Medical School of Nanjing University, Nanjing, China.
  • Hu W; Departments of Neurology and Neurosurgery, UPMC Stroke Institute, University of Pittsburgh, Pittsburgh, PA, USA.
Int J Stroke ; 17(7): 815-819, 2022 08.
Article em En | MEDLINE | ID: mdl-35102797
ABSTRACT
BACKGROUND AND

HYPOTHESIS:

Recently, two multicenter randomized controlled trials (RCT) failed to show a significantly beneficial effect of endovascular treatment (EVT) in patients with acute basilar artery occlusion (BAO). However, both trials suffered from equipoise issues which may have hindered the validity of the trial results. Therefore, additional RCT studies are needed to explore the potential benefit of EVT in patients presenting with BAO. STUDY

DESIGN:

ATTENTION is an investigator-initiated, multicenter, prospective, randomized, controlled clinical trial with open-label treatment and blinded outcome assessment (PROBE) of EVT versus best medical management (BMM). The primary effect parameter is a modified Rankin Score of 0-3 at day 90.

DISCUSSION:

ATTENTION will provide evidence for the efficacy and safety of EVT in stroke patients within 12 h after BAO. TRIAL REGISTRATION ClinicalTrials.gov NCT04751708.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Arteriopatias Oclusivas / Acidente Vascular Cerebral / Procedimentos Endovasculares Tipo de estudo: Clinical_trials / Etiology_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Arteriopatias Oclusivas / Acidente Vascular Cerebral / Procedimentos Endovasculares Tipo de estudo: Clinical_trials / Etiology_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article