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Discovery of Non-Nucleotide Small-Molecule STING Agonists via Chemotype Hybridization.
Cherney, Emily C; Zhang, Liping; Lo, Julian; Huynh, Tram; Wei, Donna; Ahuja, Vijay; Quesnelle, Claude; Schieven, Gary L; Futran, Alan; Locke, Gregory A; Lin, Zeyu; Monereau, Laura; Chaudhry, Charu; Blum, Jordan; Li, Sha; Fereshteh, Mark; Li-Wang, Bifang; Gangwar, Sanjeev; Pan, Chin; Chong, Colin; Zhu, Xiao; Posy, Shana L; Sack, John S; Zhang, Ping; Ruzanov, Max; Harner, Mary; Akhtar, Fahad; Schroeder, Gretchen M; Vite, Gregory; Fink, Brian.
Afiliação
  • Cherney EC; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.
  • Zhang L; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.
  • Lo J; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.
  • Huynh T; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.
  • Wei D; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.
  • Ahuja V; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.
  • Quesnelle C; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.
  • Schieven GL; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.
  • Futran A; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.
  • Locke GA; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.
  • Lin Z; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.
  • Monereau L; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.
  • Chaudhry C; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.
  • Blum J; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.
  • Li S; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.
  • Fereshteh M; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.
  • Li-Wang B; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.
  • Gangwar S; Bristol Myers Squibb Research and Development, 700 Bay Rd, Redwood City, California 94063, United States.
  • Pan C; Bristol Myers Squibb Research and Development, 700 Bay Rd, Redwood City, California 94063, United States.
  • Chong C; Bristol Myers Squibb Research and Development, 700 Bay Rd, Redwood City, California 94063, United States.
  • Zhu X; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.
  • Posy SL; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.
  • Sack JS; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.
  • Zhang P; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.
  • Ruzanov M; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.
  • Harner M; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.
  • Akhtar F; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.
  • Schroeder GM; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.
  • Vite G; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.
  • Fink B; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.
J Med Chem ; 65(4): 3518-3538, 2022 02 24.
Article em En | MEDLINE | ID: mdl-35108011

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Membrana Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Membrana Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article