A distinct hypothalamus-to-ß cell circuit modulates insulin secretion.

Papazoglou, Ioannis; Lee, Ji-Hyeon; Cui, Zhenzhong; Li, Chia; Fulgenzi, Gianluca; Bahn, Young Jae; Staniszewska-Goraczniak, Halina M; Piñol, Ramón A; Hogue, Ian B; Enquist, Lynn W; Krashes, Michael J; Rane, Sushil G

Papazoglou, Ioannis; Lee, Ji-Hyeon; Cui, Zhenzhong; Li, Chia; Fulgenzi, Gianluca; Bahn, Young Jae; Staniszewska-Goraczniak, Halina M; Piñol, Ramón A; Hogue, Ian B; Enquist, Lynn W; Krashes, Michael J; Rane, Sushil G.

Afiliação

Papazoglou I; Diabetes, Endocrinology and Obesity Branch, NIDDK, NIH, Bethesda, MD, USA. Electronic address: papioann@protonmail.com.
Lee JH; Diabetes, Endocrinology and Obesity Branch, NIDDK, NIH, Bethesda, MD, USA.
Cui Z; Diabetes, Endocrinology and Obesity Branch, NIDDK, NIH, Bethesda, MD, USA.
Li C; Diabetes, Endocrinology and Obesity Branch, NIDDK, NIH, Bethesda, MD, USA.
Fulgenzi G; Neural Development Section, MCGP, CCR, NCI, NIH, Frederick, MD, USA; Department of Molecular and Clinical Sciences, Marche Polytechnic University, Ancona, Italy.
Bahn YJ; Diabetes, Endocrinology and Obesity Branch, NIDDK, NIH, Bethesda, MD, USA.
Staniszewska-Goraczniak HM; Department of Molecular Biology, Princeton University, Princeton, NJ, USA.
Piñol RA; Diabetes, Endocrinology and Obesity Branch, NIDDK, NIH, Bethesda, MD, USA.
Hogue IB; Center for Immunotherapy, Vaccines, and Virotherapy, Biodesign Institute, School of Life Sciences, Arizona State University, Tempe, AZ, USA.
Enquist LW; Department of Molecular Biology, Princeton University, Princeton, NJ, USA.
Krashes MJ; Diabetes, Endocrinology and Obesity Branch, NIDDK, NIH, Bethesda, MD, USA.
Rane SG; Diabetes, Endocrinology and Obesity Branch, NIDDK, NIH, Bethesda, MD, USA. Electronic address: ranes@nih.gov.

Cell Metab ; 34(2): 285-298.e7, 2022 02 01.

Article em En | MEDLINE | ID: mdl-35108515

Assuntos

Células Secretoras de Insulina; Animais; Hipotálamo/metabolismo; Secreção de Insulina; Células Secretoras de Insulina/metabolismo; Camundongos; Ocitocina/metabolismo; Núcleo Hipotalâmico Paraventricular/metabolismo

Palavras-chave

central nervous system; glucoprivation; hypoglycemia; insulin secretion; oxytocin neurons; pancreatic ß cells; paraventricular hypothalamic nucleus; pseudorabies tracing; sympathetic innervation; transneuronal circuit

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células Secretoras de Insulina Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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