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IRS1 phosphorylation underlies the non-stochastic probability of cancer cells to persist during EGFR inhibition therapy.
Jacob Berger, Adi; Gigi, Elinor; Kupershmidt, Lana; Meir, Zohar; Gavert, Nancy; Zwang, Yaara; Prior, Amir; Gilad, Shlomit; Harush, Uzi; Haviv, Izhak; Stemmer, Salomon M; Blum, Galia; Merquiol, Emmanuelle; Mardamshina, Mariya; Kaminski Strauss, Sivan; Friedlander, Gilgi; Bar, Jair; Kamer, Iris; Reizel, Yitzhak; Geiger, Tamar; Pilpel, Yitzhak; Levin, Yishai; Tanay, Amos; Barzel, Baruch; Reuveni, Hadas; Straussman, Ravid.
Afiliação
  • Jacob Berger A; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
  • Gigi E; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
  • Kupershmidt L; TyrNovo Ltd, Rehovot, Israel.
  • Meir Z; Cancer Personalized Medicine and Diagnostic Genomics Lab, Azrieli Faculty of Medicine in the Galilee, Bar-Ilan University, Safed, Israel.
  • Gavert N; Department of Biological Regulation, Weizmann Institute of Science, Rehovot, Israel.
  • Zwang Y; Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel.
  • Prior A; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
  • Gilad S; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
  • Harush U; De Botton Institute for Protein Profiling, The Nancy and Stephen Grand Israel National Center for Personalized Medicine, Weizmann Institute of Science, Rehovot, Israel.
  • Haviv I; The Nancy and Stephen Grand Israel National Center for Personalized Medicine, Weizmann Institute of Science, Rehovot, Israel.
  • Stemmer SM; Department of Mathematics, Bar-Ilan University, Ramat-Gan, Israel.
  • Blum G; Gonda Multidisciplinary Brain Research Center, Bar-Ilan University, Ramat-Gan, Israel.
  • Merquiol E; TyrNovo Ltd, Rehovot, Israel.
  • Mardamshina M; Cancer Personalized Medicine and Diagnostic Genomics Lab, Azrieli Faculty of Medicine in the Galilee, Bar-Ilan University, Safed, Israel.
  • Kaminski Strauss S; AID Genomics and Gensort Ltd, Rehovot, Israel.
  • Friedlander G; Davidoff Center, Rabin Medical Center, Felsenstien Medical Research Center, Petach Tikva, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
  • Bar J; Institute of Drug Research, The School of Pharmacy, Faculty of Medicine, Campus Ein Karem, The Hebrew University, Jerusalem, Israel.
  • Kamer I; Institute of Drug Research, The School of Pharmacy, Faculty of Medicine, Campus Ein Karem, The Hebrew University, Jerusalem, Israel.
  • Reizel Y; Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
  • Geiger T; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
  • Pilpel Y; Ilana and Pascal Mantoux Institute for Bioinformatics, The Nancy and Stephen Grand Israel National Center for Personalized Medicine, Weizmann Institute of Science, Rehovot, Israel.
  • Levin Y; Sheba Medical Center, Ramat Gan, Israel.
  • Tanay A; Sheba Medical Center, Ramat Gan, Israel.
  • Barzel B; Department of Genetics and Institute for Diabetes Obesity and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Reuveni H; Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
  • Straussman R; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
Nat Cancer ; 2(10): 1055-1070, 2021 10.
Article em En | MEDLINE | ID: mdl-35121883
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores ErbB / Neoplasias Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores ErbB / Neoplasias Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2021 Tipo de documento: Article