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Targeting purine synthesis in ASS1-expressing tumors enhances the response to immune checkpoint inhibitors.
Keshet, Rom; Lee, Joo Sang; Adler, Lital; Iraqi, Muhammed; Ariav, Yarden; Lim, Lisha Qiu Jin; Lerner, Shaul; Rabinovich, Shiran; Oren, Roni; Katzir, Rotem; Weiss Tishler, Hila; Stettner, Noa; Goldman, Omer; Landesman, Hadas; Galai, Sivan; Kuperman, Yael; Kuznetsov, Yuri; Brandis, Alexander; Mehlman, Tevi; Malitsky, Sergey; Itkin, Maxim; Koehler, S Eleonore; Zhao, Yongmei; Talsania, Keyur; Shen, Tsai-Wei; Peled, Nir; Ulitsky, Igor; Porgador, Angel; Ruppin, Eytan; Erez, Ayelet.
Afiliação
  • Keshet R; Department of Biological Regulation, Weizmann Institute of Science, Rehovot, Israel.
  • Lee JS; The Bert W. Strassburger Lipid Center, Sheba Medical Center, Tel Hashomer, Israel.
  • Adler L; Cancer Data Science Lab, National Cancer Institutes of Health, Bethesda, MD, USA.
  • Iraqi M; Department of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences & Technology, Samsung Medical Center, Sungkyunkwan University, Seoul, Republic of Korea.
  • Ariav Y; Department of Precision Medicine, School of Medicine, Sungkyunkwan University, Suwon, Republic of Korea.
  • Lim LQJ; Department of Biological Regulation, Weizmann Institute of Science, Rehovot, Israel.
  • Lerner S; Faculty of Health Sciences, The Shraga Segal Department of Microbiology, Immunology and Genetics, Ben-Gurion University of the Negev, Beer Sheva, Israel.
  • Rabinovich S; Department of Biological Regulation, Weizmann Institute of Science, Rehovot, Israel.
  • Oren R; Department of Biological Regulation, Weizmann Institute of Science, Rehovot, Israel.
  • Katzir R; Department of Biological Regulation, Weizmann Institute of Science, Rehovot, Israel.
  • Weiss Tishler H; Department of Biological Regulation, Weizmann Institute of Science, Rehovot, Israel.
  • Stettner N; Department of Veterinary Resources, Weizmann Institute of Science, Rehovot, Israel.
  • Goldman O; Cancer Data Science Lab, National Cancer Institutes of Health, Bethesda, MD, USA.
  • Landesman H; Department of Biological Regulation, Weizmann Institute of Science, Rehovot, Israel.
  • Galai S; Department of Biological Regulation, Weizmann Institute of Science, Rehovot, Israel.
  • Kuperman Y; Department of Veterinary Resources, Weizmann Institute of Science, Rehovot, Israel.
  • Kuznetsov Y; Department of Biological Regulation, Weizmann Institute of Science, Rehovot, Israel.
  • Brandis A; Department of Biological Regulation, Weizmann Institute of Science, Rehovot, Israel.
  • Mehlman T; Department of Biological Regulation, Weizmann Institute of Science, Rehovot, Israel.
  • Malitsky S; Department of Veterinary Resources, Weizmann Institute of Science, Rehovot, Israel.
  • Itkin M; Department of Veterinary Resources, Weizmann Institute of Science, Rehovot, Israel.
  • Koehler SE; Department of Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot, Israel.
  • Zhao Y; Department of Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot, Israel.
  • Talsania K; Department of Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot, Israel.
  • Shen TW; Department of Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot, Israel.
  • Peled N; Department Anatomy & Embryology, Maastricht University, Maastricht, the Netherlands.
  • Ulitsky I; Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
  • Porgador A; Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
  • Ruppin E; Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
  • Erez A; The Legacy Heritage Oncology Center and Dr. Larry Norton Institute, Soroka Medical Center and Ben-Gurion University, Beer-Sheva, Israel.
Nat Cancer ; 1(9): 894-908, 2020 09.
Article em En | MEDLINE | ID: mdl-35121952
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Argininossuccinato Sintase / Neoplasias da Mama Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Argininossuccinato Sintase / Neoplasias da Mama Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article