MALAT-1/p53/miR-155/miR-146a ceRNA circuit tuned by methoxylated quercitin glycoside alters immunogenic and oncogenic profiles of breast cancer.

Abdel-Latif, Mustafa; Riad, Ahmed; Soliman, Raghda A; Elkhouly, Aisha M; Nafae, Heba; Gad, Mohamed Z; Motaal, Amira Abdel; Youness, Rana A

Abdel-Latif, Mustafa; Riad, Ahmed; Soliman, Raghda A; Elkhouly, Aisha M; Nafae, Heba; Gad, Mohamed Z; Motaal, Amira Abdel; Youness, Rana A.

Afiliação

Abdel-Latif M; Molecular Genetics Research Team (MGRT), Biotechnology Program, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo, Egypt.
Riad A; Molecular Genetics Research Team (MGRT), Pharmaceutical Biology Department, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo, Egypt.
Soliman RA; Molecular Genetics Research Team (MGRT), Biotechnology Program, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo, Egypt.
Elkhouly AM; Molecular Genetics Research Team (MGRT), Pharmaceutical Biology Department, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo, Egypt.
Nafae H; Molecular Genetics Research Team (MGRT), Pharmaceutical Biology Department, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo, Egypt.
Gad MZ; Molecular Genetics Research Team (MGRT), Pharmaceutical Biology Department, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo, Egypt.
Motaal AA; Department of Biochemistry, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo, Egypt.
Youness RA; Molecular Genetics Research Team (MGRT), Pharmaceutical Biology Department, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo, Egypt.

Mol Cell Biochem ; 477(4): 1281-1293, 2022 Apr.

Article em En | MEDLINE | ID: mdl-35129780

Assuntos

Glicosídeos/farmacologia; MicroRNAs/imunologia; RNA Longo não Codificante/imunologia; RNA Neoplásico/imunologia; Neoplasias de Mama Triplo Negativas/imunologia; Proteína Supressora de Tumor p53/imunologia; Feminino; Humanos; Células MCF-7; MicroRNAs/genética; RNA Longo não Codificante/genética; RNA Neoplásico/genética; Neoplasias de Mama Triplo Negativas/tratamento farmacológico; Neoplasias de Mama Triplo Negativas/genética; Proteína Supressora de Tumor p53/genética

Palavras-chave

Breast cancer; Cleome droserifolia; MALAT-1; Natural Killer cells; Tumor microenvironment; miR-146a; miR-155

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA Neoplásico / Proteína Supressora de Tumor p53 / MicroRNAs / RNA Longo não Codificante / Neoplasias de Mama Triplo Negativas / Glicosídeos Limite: Female / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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