Collagenous Colitis Possibly Associated with Dipeptidyl Peptidase-4 Inhibitor.
Intern Med
; 61(18): 2731-2734, 2022 Sep 15.
Article
em En
| MEDLINE
| ID: mdl-35135927
ABSTRACT
A 60-year-old man with type 2 diabetes mellitus treated with a dipeptidyl peptidase-4 (DPP-4) inhibitor was referred to our hospital because of his refractory watery diarrhea. Ileocolonoscopy revealed increased capillary growth, fine granular mucosa, and longitudinal mucosal tears mainly in the left side of the colon. A bioptic examination revealed thickened subepithelial collagen bands, thus confirming the diagnosis of collagenous colitis. Systemic steroid therapy was initiated, but his symptoms recurred when tapering the steroid. However, withdrawal of the DPP-4 inhibitor was successful even after the cessation of steroid therapy. We therefore considered his collagenous colitis to have been caused by the DPP-4 inhibitor.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Colite
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Colite Colagenosa
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Diabetes Mellitus Tipo 2
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Inibidores da Dipeptidil Peptidase IV
Tipo de estudo:
Diagnostic_studies
/
Risk_factors_studies
Limite:
Humans
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Male
/
Middle aged
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article