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Identification of the nucleotide-free state as a therapeutic vulnerability for inhibition of selected oncogenic RAS mutants.
Khan, Imran; Koide, Akiko; Zuberi, Mariyam; Ketavarapu, Gayatri; Denbaum, Eric; Teng, Kai Wen; Rhett, J Matthew; Spencer-Smith, Russell; Hobbs, G Aaron; Camp, Ernest Ramsay; Koide, Shohei; O'Bryan, John P.
Afiliação
  • Khan I; Department of Cell and Molecular Pharmacology and Experimental Therapeutics, Medical University of South Carolina, Charleston, SC 29425, USA; Hollings Cancer Center, Medical University of South Carolina, Charleston, SC 29425, USA; Ralph H. Johnson VA Medical Center, Charleston, SC 29401, USA; Depart
  • Koide A; Perlmutter Cancer Center, New York University Langone Health, New York, NY 10016, USA; Department of Medicine, New York University School of Medicine, New York, NY 10016, USA.
  • Zuberi M; Department of Cell and Molecular Pharmacology and Experimental Therapeutics, Medical University of South Carolina, Charleston, SC 29425, USA; Hollings Cancer Center, Medical University of South Carolina, Charleston, SC 29425, USA.
  • Ketavarapu G; Perlmutter Cancer Center, New York University Langone Health, New York, NY 10016, USA.
  • Denbaum E; Perlmutter Cancer Center, New York University Langone Health, New York, NY 10016, USA.
  • Teng KW; Perlmutter Cancer Center, New York University Langone Health, New York, NY 10016, USA.
  • Rhett JM; Department of Cell and Molecular Pharmacology and Experimental Therapeutics, Medical University of South Carolina, Charleston, SC 29425, USA; Hollings Cancer Center, Medical University of South Carolina, Charleston, SC 29425, USA.
  • Spencer-Smith R; Department of Pharmacology, University of Illinois at Chicago, Chicago, IL 60612, USA.
  • Hobbs GA; Department of Cell and Molecular Pharmacology and Experimental Therapeutics, Medical University of South Carolina, Charleston, SC 29425, USA; Hollings Cancer Center, Medical University of South Carolina, Charleston, SC 29425, USA.
  • Camp ER; Department of Surgery, Medical University of South Carolina, Charleston, SC 29425, USA; Hollings Cancer Center, Medical University of South Carolina, Charleston, SC 29425, USA; Ralph H. Johnson VA Medical Center, Charleston, SC 29401, USA.
  • Koide S; Perlmutter Cancer Center, New York University Langone Health, New York, NY 10016, USA; Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY 10016, USA. Electronic address: shohei.koide@nyulangone.org.
  • O'Bryan JP; Department of Cell and Molecular Pharmacology and Experimental Therapeutics, Medical University of South Carolina, Charleston, SC 29425, USA; Hollings Cancer Center, Medical University of South Carolina, Charleston, SC 29425, USA; Ralph H. Johnson VA Medical Center, Charleston, SC 29401, USA; Depart
Cell Rep ; 38(6): 110322, 2022 02 08.
Article em En | MEDLINE | ID: mdl-35139380
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Genes ras / Mutação / Nucleotídeos Tipo de estudo: Diagnostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Genes ras / Mutação / Nucleotídeos Tipo de estudo: Diagnostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article