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Exploring protective and risk factors in the home environment in high-risk families - results from the Danish High Risk and Resilience Study-VIA 7.
Thorup, Anne Amalie Elgaard; Gantriis, Ditte Lou; Greve, Aja Neergaard; Henriksen, Maria Toft; Zahle, Kate Kold; Stadsgaard, Henriette; Ellersgaard, Ditte; Burton, Birgitte Klee; Christiani, Camilla Jerlang; Spang, Katrine; Hemager, Nicoline; Jepsen, Jens Richardt Møllegaard; Plessen, Kerstin J; Nordentoft, Merete; Mors, Ole; Bliksted, Vibeke.
Afiliação
  • Thorup AAE; The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark. anne.amalie.elgaard.thorup@regionh.dk.
  • Gantriis DL; Child and Adolescent Mental Health Center, Mental Health Services, Capital Region of Denmark, University of Copenhagen, Copenhagen, Denmark. anne.amalie.elgaard.thorup@regionh.dk.
  • Greve AN; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. anne.amalie.elgaard.thorup@regionh.dk.
  • Henriksen MT; The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark.
  • Zahle KK; Psychosis Research Unit, Aarhus University Hospital Skejby Psychiatry, Aarhus, Denmark.
  • Stadsgaard H; The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark.
  • Ellersgaard D; Psychosis Research Unit, Aarhus University Hospital Skejby Psychiatry, Aarhus, Denmark.
  • Burton BK; The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark.
  • Christiani CJ; Psychosis Research Unit, Aarhus University Hospital Skejby Psychiatry, Aarhus, Denmark.
  • Spang K; The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark.
  • Hemager N; Psychosis Research Unit, Aarhus University Hospital Skejby Psychiatry, Aarhus, Denmark.
  • Jepsen JRM; The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark.
  • Plessen KJ; Psychosis Research Unit, Aarhus University Hospital Skejby Psychiatry, Aarhus, Denmark.
  • Nordentoft M; The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark.
  • Mors O; Centre for Neuropsychiatric Schizophrenia Research & Centre for Clinical Intervention and Neuropsychiatric Schizophrenia Research, Copenhagen University Hospital, Copenhagen, Denmark.
  • Bliksted V; The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus, Denmark.
BMC Psychiatry ; 22(1): 100, 2022 02 09.
Article em En | MEDLINE | ID: mdl-35139818
BACKGROUND: Exposure to inadequate home environment may put the healthy development of familial high-risk children at risk. This study aimed to investigate associations between risk factors and an adequate home environment of children having a parent diagnosed with schizophrenia or bipolar disorder. METHODS: From a cohort of 522 children, data from 463 7-year-old children was included. Of these 172 children had familial risk for schizophrenia, 109 children had familial risk for bipolar disorder, and 190 were population-based controls. As part of a comprehensive battery, all participants were assessed with the Middle Childhood-Home Observation for Measurement of the Environment Inventory (MC-HOME Inventory) measuring the quality of the home environment. RESULTS: When analyzing all families together, we found that having a parent diagnosed with schizophrenia would have a negative impact on the home environment (ß = -1.08; 95% CI (-2.16;-0.01); p = 0.05), while familial risk for bipolar disorder did not show significant predictive value. Being a single caregiver and child having experienced severe life events from ages 4 to 7 showed significant negative impact, while child having a mental illness diagnosis did not. Being a female caregiver, good social functioning of the caregiver, high child IQ and not being a single caregiver were found to predict positive values for the home environment. We found similar results when analyzing caregivers with and without a diagnosis separately. CONCLUSIONS: Knowledge of what predicts good home environment should be used to inform development of early interventions for families at risk.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transtorno Bipolar / Predisposição Genética para Doença Tipo de estudo: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Child / Child, preschool / Female / Humans País/Região como assunto: Europa Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transtorno Bipolar / Predisposição Genética para Doença Tipo de estudo: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Child / Child, preschool / Female / Humans País/Região como assunto: Europa Idioma: En Ano de publicação: 2022 Tipo de documento: Article