Comparative genomic and transcriptomic analysis guides to further enhance the biosynthesis of erythromycin by an overproducer.

Li, Xiaobo; Ke, Xiang; Qiao, Lijia; Sui, Yufei; Chu, Ju

Li, Xiaobo; Ke, Xiang; Qiao, Lijia; Sui, Yufei; Chu, Ju.

Afiliação

Li X; State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.
Ke X; State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.
Qiao L; State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.
Sui Y; State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.
Chu J; State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.

Biotechnol Bioeng ; 119(6): 1624-1640, 2022 06.

Article em En | MEDLINE | ID: mdl-35150130

Assuntos

Eritromicina; Saccharopolyspora; Proteínas de Bactérias/genética; Eritromicina/metabolismo; Genômica; Complexo Cetoglutarato Desidrogenase/genética; Complexo Cetoglutarato Desidrogenase/metabolismo; Ácidos Cetoglutáricos/metabolismo; Saccharopolyspora/genética; Saccharopolyspora/metabolismo; Transcriptoma/genética

Palavras-chave

2-oxoglutarate; Saccharopolyspora erythraea; comparative omics; erythromycin; metabolic engineering

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Eritromicina / Saccharopolyspora Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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