A Mild Two-Step Synthesis of Structurally Valuable Indole-Fused Derivatives.
J Org Chem
; 87(5): 3212-3222, 2022 03 04.
Article
em En
| MEDLINE
| ID: mdl-35152695
ABSTRACT
A mild two-step synthetic approach for the preparation of structurally valuable indolo[3',2'4,5]pyrrolo[3,2,1-kl]phenothiazines has been developed. In this work, cyclohexanone was used as the key bridge to connect the indole and phenothiazine frameworks to construct a structurally valuable indole-fused derivative. The present protocol achieved the cascade construction of multiple C-hetero bonds, affording a convenient approach access to hexacyclic-fused system that contained both indole and phenothiazine, two privileged skeletons.
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1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Indóis
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article