Risk Factors for Female Breast Cancer: A Population Cohort Study.
Cancers (Basel)
; 14(3)2022 Feb 03.
Article
em En
| MEDLINE
| ID: mdl-35159055
ABSTRACT
BACKGROUND:
The incidence of female BC among the Eastern and Southeastern Asian populations has gradually increased in recent years. However, epidemiological studies on the relationship between a sedentary lifestyle and female BC are insufficient. In order to determine the association between this lifestyle and the incidence of female BC, we conducted a population-based cohort study on women in Taiwan.METHODS:
We followed a prospective cohort of 5879 women aged 30 years and over enrolled in the 2001 National Health Interview Survey (NHIS), who developed female BC over a period of 72,453 person years, and we estimated the hazard ratios (HRs) and corresponding 95% confidence intervals (CIs) using the Cox proportional hazards model.RESULTS:
RFs associated with female BC incidence included parity (adjusted HR = 0.63; 95% CI 0.44-0.91), body mass index (adjusted HR = 1.34; 95% CI 1.04-1.71), and ≥3 h/day spent sitting (adjusted HR = 1.89; 95% CI 1.08-3.32). The incidence of female BC in participants who sat for ≥3 h/day and consumed sugary drinks was 2.5 times greater than that in those who sat for <3 h/day and did not consume sugary drinks (adjusted HR = 2.51; 95% CI 1.01-6.23).CONCLUSIONS:
The findings of this study indicate that sedentary behavior and sugary drink intake may increase the risk of developing female BC. These are modifiable RFs; therefore, a healthy lifestyle and diet can reduce the incidence of female BC.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article