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Infections with highly pathogenic avian influenza A virus (HPAIV) H5N8 in harbor seals at the German North Sea coast, 2021.
Postel, Alexander; King, Jacqueline; Kaiser, Franziska K; Kennedy, Johanna; Lombardo, Mara Sophie; Reineking, Wencke; de le Roi, Madeleine; Harder, Timm; Pohlmann, Anne; Gerlach, Thomas; Rimmelzwaan, Guus; Rohner, Simon; Striewe, Lotte C; Gross, Stephanie; Schick, Luca A; Klink, Jana C; Kramer, Katharina; Osterhaus, Albert D M E; Beer, Martin; Baumgärtner, Wolfgang; Siebert, Ursula; Becher, Paul.
Afiliação
  • Postel A; Institute of Virology, University of Veterinary Medicine, Hannover, Germany.
  • King J; Institute of Diagnostic Virology, Friedrich-Loeffler-Institute, Greifswald, Germany.
  • Kaiser FK; Research Center for Emerging Infections and Zoonoses, University of Veterinary Medicine, Hannover, Germany.
  • Kennedy J; Institute of Virology, University of Veterinary Medicine, Hannover, Germany.
  • Lombardo MS; Institute of Pathology, University of Veterinary Medicine, Hannover, Germany.
  • Reineking W; Institute of Pathology, University of Veterinary Medicine, Hannover, Germany.
  • de le Roi M; Institute of Pathology, University of Veterinary Medicine, Hannover, Germany.
  • Harder T; Institute of Diagnostic Virology, Friedrich-Loeffler-Institute, Greifswald, Germany.
  • Pohlmann A; Institute of Diagnostic Virology, Friedrich-Loeffler-Institute, Greifswald, Germany.
  • Gerlach T; Research Center for Emerging Infections and Zoonoses, University of Veterinary Medicine, Hannover, Germany.
  • Rimmelzwaan G; Research Center for Emerging Infections and Zoonoses, University of Veterinary Medicine, Hannover, Germany.
  • Rohner S; Institute for Terrestrial and Aquatic Wildlife Research, University of Veterinary Medicine, Hannover, Germany.
  • Striewe LC; Institute for Terrestrial and Aquatic Wildlife Research, University of Veterinary Medicine, Hannover, Germany.
  • Gross S; Institute for Terrestrial and Aquatic Wildlife Research, University of Veterinary Medicine, Hannover, Germany.
  • Schick LA; Institute for Terrestrial and Aquatic Wildlife Research, University of Veterinary Medicine, Hannover, Germany.
  • Klink JC; Institute for Terrestrial and Aquatic Wildlife Research, University of Veterinary Medicine, Hannover, Germany.
  • Kramer K; Landeslabor Schleswig- Holstein, Neumünster, Germany.
  • Osterhaus ADME; Research Center for Emerging Infections and Zoonoses, University of Veterinary Medicine, Hannover, Germany.
  • Beer M; Institute of Diagnostic Virology, Friedrich-Loeffler-Institute, Greifswald, Germany.
  • Baumgärtner W; Institute of Pathology, University of Veterinary Medicine, Hannover, Germany.
  • Siebert U; Institute for Terrestrial and Aquatic Wildlife Research, University of Veterinary Medicine, Hannover, Germany.
  • Becher P; Institute of Virology, University of Veterinary Medicine, Hannover, Germany.
Emerg Microbes Infect ; 11(1): 725-729, 2022 Dec.
Article em En | MEDLINE | ID: mdl-35172704
In brain tissue of three harbor seals of the German North Sea coast, high virus loads of highly pathogenic avian influenza virus (HPAIV) H5N8 were detected. Identification of different virus variants indicates high exposure to HPAIV circulating in wild birds, but there is no evidence for H5 specific antibodies in healthy seals. Replication of avian viruses in seals may allow HPAIV to acquire mutations needed to adapt to mammalian hosts as shown by PB2 627K variants detected in these cases.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vírus da Influenza A / Phoca / Vírus da Influenza A Subtipo H5N8 / Influenza Aviária Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vírus da Influenza A / Phoca / Vírus da Influenza A Subtipo H5N8 / Influenza Aviária Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article