Icariin inhibits RANKL-induced osteoclastogenesis in RAW264.7 cells via inhibition of reactive oxygen species production by reducing the expression of NOX1 and NOX4.

Ji, Ruifeng; Wu, Dou; Liu, Qiang

Icariin inhibits RANKL-induced osteoclastogenesis in RAW264.7 cells via inhibition of reactive oxygen species production by reducing the expression of NOX1 and NOX4.

Ji, Ruifeng; Wu, Dou; Liu, Qiang.

Afiliação

Ji R; Department of Orthopedics, Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences Tongji Shanxi Hospital, Taiyuan, 030032, China.
Wu D; Department of Orthopedics, Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences Tongji Shanxi Hospital, Taiyuan, 030032, China.
Liu Q; Department of Orthopedics, Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences Tongji Shanxi Hospital, Taiyuan, 030032, China. Electronic address: sxdyy001@163.com.

Biochem Biophys Res Commun ; 600: 6-13, 2022 04 16.

Article em En | MEDLINE | ID: mdl-35182975

Assuntos

Osteogênese; Ligante RANK; Animais; Diferenciação Celular; Flavonoides; Ligantes; Camundongos; NADPH Oxidase 4/metabolismo; NF-kappa B/metabolismo; Osteoclastos/metabolismo; Ligante RANK/metabolismo; Células RAW 264.7; Espécies Reativas de Oxigênio/metabolismo

Palavras-chave

Icariin; Osteoclastogenesis; Reactive oxygen species

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteogênese / Ligante RANK Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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